SCHEMBL3912820

SCHEMBL3912820

CN(C)C(=Cc1ccccc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.55
AKR1C1 Q04828 1/20 0.48
HTT P42858 1/20 0.46
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
RECQL P46063 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TP53 P04637 1/20 0.42
MTNR1A P48039 2/20 0.42
MTNR1B P49286 2/20 0.42
FBP1 P09467 1/20 0.41
GLA P06280 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TRPM8 Q7Z2W7 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11139540 0.88 ALDH1A1 (0.50) AKR1C3AKR1C1HTTALDH1A1TSHR
SCHEMBL3937738 0.86 AKR1C3 (0.53) AKR1C3AKR1C1HTTALDH1A1TSHR
SCHEMBL7677075 0.84 MCL1 (0.49) AKR1C3AKR1C1HTTALDH1A1TSHR
SCHEMBL9099207 0.82 ALDH1A1 (0.50) AKR1C3AKR1C1HTTALDH1A1RECQL
SCHEMBL815584 0.82 ALDH1A1 (0.50) AKR1C3AKR1C1HTTALDH1A1RECQL
SCHEMBL11160065 0.80 AKR1C3 (0.57) AKR1C3AKR1C1HTTALDH1A1TSHR
SCHEMBL4729447 0.79 NPC1 (0.54) AKR1C3AKR1C1HTTALDH1A1CYP3A4
SCHEMBL5712174 0.78 TRPM8 (0.56) AKR1C3AKR1C1HTTALDH1A1TSHR
SCHEMBL9587353 0.77 MEN1 (0.68) ALDH1A1CYP2C9MEN1KMT2ATDP1
SCHEMBL9587350 0.77 MEN1 (0.68) ALDH1A1CYP2C9MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2003638-A None JP disclosed
CN-118344248-A 20-Deoxyingenol ether derivative with anti-tumor activity and preparation and application thereof 沈阳药科大学 2024-07-16 CN disclosed
WO-2024130161-A2 NOVEL CAMPTOTHECIN DERIVATIVES AND CONJUGATES THEREOF BIONECURE THERAPEUTICS INC (US) 2024-06-20 WO disclosed
EP-2768325-A1 PRESERVATIVE COMBINATIONS COMPRISING PROPIONIC ACID AND VANILLIN AND/OR CINNAMIC ACID Purac Biochem bv (NL) 2014-08-27 EP disclosed
EP-2768326-A1 PRESERVATIVE COMBINATIONS Purac Biochem bv (NL) 2014-08-27 EP disclosed
WO-2013058651-A1 PRESERVATIVE COMBINATIONS PURAC BIOCHEM B.V. (NL) 2013-04-25 WO disclosed
WO-2013058650-A1 PRESERVATIVE COMBINATIONS COMPRISING PROPIONIC ACID AND VANILLIN AND/OR CINNAMIC ACID PURAC BIOCHEM B.V. (NL) 2013-04-25 WO disclosed
WO-2013056572-A1 METHOD FOR RAPIDLY MEASURING MELATONIN ADULTERATION OF CHINESE PATENT MEDICINE OR HEALTHCARE FOOD 深圳市药品检验所 (CN) 2013-04-25 WO disclosed
EP-2034856-A1 BEVERAGE COMPOSITIONS COMPRISING A PRESERVATIVE SYSTEM THE COCA-COLA COMPANY (US) 2009-03-18 EP disclosed
WO-2007139864-A1 BEVERAGE COMPOSITIONS COMPRISING A PRESERVATIVE SYSTEM THE COCA-COLA COMPANY (US) 2007-12-06 WO disclosed
EP-0351856-A2 Thiazolo[5,4-b]azepine compounds Takeda Chemical Industries, Ltd. (JP) 1990-01-24 EP disclosed
JP-H023638-A 1,2-BIS(DIMETHYLAMINOCINNAMOYLOXY)PROPANE DERIVATIVE AND ULTRAVIOLET LIGHT ABSORBER CONTAINING THE SAME DERIVATIVE PIAS ARISE KK 1990-01-09 JP disclosed
US-4592906-A Ester of p-dimethylaminocinnamic acid GRAESSER LABORATORIES, LTD. (GB) 1986-06-03 US disclosed
EP-0153089-A1 Ultra-violet absorbing compounds and compositions containing said compounds GRAESSER LABORATORIES LIMITED (GB) 1985-08-28 EP disclosed