Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18270572 | 1.00 | LMNA (0.42) | LMNATSHRSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL18270561 | 1.00 | LMNA (0.42) | LMNATSHRSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6900329 | 0.86 | LMNA (0.48) | LMNATSHRALDH1A1TDP1CYP3A4 | |
| SCHEMBL7223143 | 0.85 | CA1 (0.55) | LMNAFDPSCA1FAAH | |
| SCHEMBL9012298 | 0.84 | FAAH (0.44) | TSHRSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL3910294 | 0.84 | LMNA (0.71) | LMNATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL28311582 | 0.83 | LMNA (0.55) | LMNAFDPSCA1FAAH | |
| SCHEMBL7218183 | 0.83 | LMNA (0.55) | LMNAFDPSCA1FAAH | |
| Hydrochloric Acid SCHEMBL28164871 | 0.83 | CA1 (0.53) | LMNAFDPSCA1FAAH | |
| SCHEMBL26020483 | 0.82 | LMNA (0.34) | LMNATSHRSMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9362595-B2 | Nonaqueous electrolytic solution and energy storage device using same | UBE INDUSTRIES, LTD. (JP) | 2016-06-07 | — | — | US | claimed |
| US-20140030609-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND ENERGY STORAGE DEVICE USING SAME | UBE INDUSTRIES, LTD. (JP) | 2014-01-30 | — | — | US | claimed |
| CN-107365262-B | A kind of preparation method of 5,5- dimethyl -2- cyano cyclopentanone | HANGZHOU UDRAGON CHEMICAL CO., LTD. (CN) | 2019-10-29 | — | — | CN | disclosed |
| CN-109810589-A | Light converts resin combination, light conversion layer folds substrate and image display device | 东友精细化工有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-109503587-A | The antitumor action of double heterocycle ribavirin analogs and application | 辽宁利锋科技开发有限公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-107365262-A | A kind of preparation method of 5,5- dimethyl -2- cyano group cyclopentanone | 杭州宇龙化工有限公司 | 2017-11-21 | — | — | CN | disclosed |
| CN-107216277-A | A kind of preparation method of LCZ696 impurity of the drug | 东南大学 | 2017-09-29 | — | — | CN | disclosed |
| US-20170267639-A1 | Process for Synthesizing Oxidized Lactam Compounds | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2017-09-21 | — | — | US | disclosed |
| US-9670200-B2 | Quaternary ammonium salt prodrugs | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |
| US-9650341-B2 | Process for synthesizing oxidized lactam compounds | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-05-16 | — | — | US | disclosed |
| US-9580417-B2 | Prodrugs of heteraromatic compounds | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-02-28 | — | — | US | disclosed |
| US-20110015156-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHOLOGICAL DISORDERS | ALKERMES, INC. | 2011-01-20 | — | — | US | disclosed |
| US-7582226-B2 | Ester-containing fluid compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-6994799-B2 | Ester-containing fluid compositions | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-02-07 | — | — | US | disclosed |
| US-20040238785-A1 | Ester-containing fluid compositions | VAN DRIESSCHE EDDY (BE) | 2004-12-02 | — | — | US | disclosed |
| US-6667285-B1 | Branched-chain carboxylic acid monoalkyl ester with outstanding hydrolytic stability | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2003-12-23 | — | — | US | disclosed |
| EP-1259471-A1 | ESTER-CONTAINING FLUID COMPOSITIONS | Exxonmobil Chemical Patents Inc. (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-1225213-A1 | LUBRICATING OIL FOR REFRIGERATOR, HYDRAULIC FLUID COMPOSITION FOR REFRIGERATOR AND METHOD FOR LUBRICATION OF REFRIGERATOR | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-20020005503-A1 | Ester-containing fluid compositions | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-01-17 | — | — | US | disclosed |
| WO-2001047858-A1 | ESTER-CONTAINING FLUID COMPOSITIONS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267639-A1 | Process for Synthesizing Oxidized Lactam Compounds | COASY, DHPS, OXA1L | LMNA 2901/4885TSHR 4488/4885SMN1; SMN2 3665/4885 |
| US-20110015156-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHOLOGICAL DISORDERS | GABBR1, GABBR2, GABRE | LMNA 1349/4885TSHR 1280/4885SMN1; SMN2 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.