SCHEMBL3912974

SCHEMBL3912974

CCO[Si](C)(OCC)OC(C)=O.[LiH]

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838934 0.98 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL3910859 0.95 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL839014 0.93 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL728906 0.88 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL16616580 0.86 ALDH1A1 (0.37) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL15066481 0.79 ALDH1A1 (0.38) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL3911401 0.78 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL728864 0.78 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL1781555 0.77 THRB (0.44) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL3919746 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 EP disclosed