⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995906 | 0.86 | CCR1 (0.34) | — | |
| SCHEMBL12987063 | 0.79 | — | — | |
| SCHEMBL9530861 | 0.78 | — | — | |
| SCHEMBL8009351 | 0.78 | — | — | |
| SCHEMBL128388 | 0.75 | NQO1 (0.46) | — | |
| SCHEMBL1404367 | 0.72 | KMT2A (0.41) | — | |
| SCHEMBL8008263 | 0.72 | CYP1A2 (0.31) | — | |
| SCHEMBL3841411 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL7996406 | 0.71 | CALM1 (0.40) | — | |
| SCHEMBL676285 | 0.71 | NR1H4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9862691-B2 | Cyclic triazo and diazo sodium channel blockers | UNIVERSITY OF GREENWICH (GB) | 2018-01-09 | — | — | US | claimed |
| US-20160311784-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIVERSITY OF GREENWICH (GB) | 2016-10-27 | — | — | US | claimed |
| EP-2035420-A2 | KV1.5 POTASSIUM CHANNEL INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2009-03-18 | — | — | EP | claimed |
| WO-2007149873-A2 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | WO | claimed |
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | US | claimed |
| EP-2035420-A2 | KV1.5 POTASSIUM CHANNEL INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007149873-A2 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | WO | disclosed |
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
| CN-1178944-C | Preparation of 4(fluorated aromatic radical) boron derivatives | ��ʽ�����ձ���ý | 2004-12-08 | — | — | CN | disclosed |
| CN-1178945-C | Prep. of boron tetra [fluoro aryl] compound | ��ʽ�����ձ���ý | 2004-12-08 | — | — | CN | disclosed |
| CN-1178943-C | Preparation of 4(fluorated aromatic radical) boron derivatives | ��ʽ�����ձ���ý | 2004-12-08 | — | — | CN | disclosed |
| CN-1092664-C | Method for producing [ fluoroaryl ] boron compound and method for producing tetrakis [ fluoroaryl ] boron derivative | NIPPON CATALYTIC CHEM IND (JP) | 2002-10-16 | — | — | CN | disclosed |
| CN-1313289-A | Preparation of 4(fluorated aromatic radical) boron derivatives | NIPPON CATALYTIC CHEM IND (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1313288-A | Preparation of 4(fluorated aromatic radical) boron derivatives | NIPPON CATALYTIC CHEM IND (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1295073-A | Prep. of boron [fluoroaryl] compound | NIPPON CATALYTIC CHEM IND (JP) | 2001-05-16 | — | — | CN | disclosed |
| CN-1295074-A | Prep. of boron tetra [fluoro aryl] compound | NIPPON CATALYTIC CHEM IND (JP) | 2001-05-16 | — | — | CN | disclosed |
| CN-1180705-A | Method for producing [ fluoroaryl ] boron compound and method for producing tetrakis [ fluoroaryl ] boron derivative | NIPPON CATALYTIC CHEM IND (JP) | 1998-05-06 | — | — | CN | disclosed |