Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913541 | 0.86 | — | — | |
| SCHEMBL1569511 | 0.83 | ESR1 (0.39) | CCR1CCR5CCR8MAPK1MAOB | |
| SCHEMBL29023056 | 0.81 | CCR1 (0.34) | CCR1CCR5CCR8MAPK1MAOB | |
| SCHEMBL17046267 | 0.81 | ALDH1A1 (0.37) | CCR1CCR5CCR8MAPK1MAOB | |
| SCHEMBL7953637 | 0.80 | MAPK1 (0.40) | CCR1CCR5CCR8MAPK1MAOB | |
| SCHEMBL6554584 | 0.80 | TUBB4A (0.39) | CCR1CCR5CCR8MAPK1LMNA | |
| SCHEMBL77754 | 0.80 | CA1 (0.39) | CCR1CCR5CCR8CA1CA2 | |
| SCHEMBL7387017 | 0.79 | TAAR1 (0.39) | MAPK1MAOBNOS3NOS1NOS2 | |
| SCHEMBL7386281 | 0.79 | ALDH1A1 (0.37) | CCR1CCR5CCR8MAPK1LMNA | |
| SCHEMBL27431792 | 0.78 | CA1 (0.38) | CCR1CCR5CCR8CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048863-A | SEXUAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-04-11 | — | — | US | disclosed |