Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902998 | 0.90 | POLB (0.50) | UTS2RSMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL3907168 | 0.87 | UTS2R (0.45) | UTS2RSMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL3906036 | 0.86 | MEN1 (0.43) | KMT2AHTTRAB9AALDH1A1MEN1 | |
| SCHEMBL3902148 | 0.85 | LMNA (0.44) | UTS2RSMN1; SMN2KMT2ARAB9AALDH1A1 | |
| SCHEMBL3906640 | 0.85 | LMNA (0.42) | SMN1; SMN2KMT2AHTTALDH1A1LMNA | |
| SCHEMBL3903926 | 0.84 | LMNA (0.40) | UTS2RSMN1; SMN2KMT2AHTTALDH1A1 | |
| SCHEMBL3903401 | 0.82 | TAS1R3 (0.45) | KMT2ARAB9ATAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL3902328 | 0.81 | UTS2R (0.46) | UTS2RSMN1; SMN2KMT2AHTTNPC1 | |
| SCHEMBL3905222 | 0.81 | GAA (0.42) | SMN1; SMN2KMT2AHTTNPC1ALDH1A1 | |
| SCHEMBL3907148 | 0.79 | SLC6A9 (0.47) | UTS2RSMN1; SMN2ALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838663-B1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LTD (GB) | 2009-01-21 | — | — | EP | claimed |
| US-20090270510-A1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | US | disclosed |
| US-20090270510-A1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | US | disclosed |
| US-20090270510-A1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | US | disclosed |
| EP-1838663-B1 | GLYCINE TRANSPORT INHIBITORS | GLAXO GROUP LTD (GB) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270510-A1 | GLYCINE TRANSPORT INHIBITORS | SLC18A2, SLC6A5, SLC1A2 | UTS2R 3095/4885SMN1; SMN2 2532/4885KMT2A 1752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.