Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 10/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.39 |
| ▸ | CCKBR | P32239 | 3/20 | 0.38 |
| ▸ | CCKAR | P32238 | 2/20 | 0.38 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12345899 | 0.85 | BRD4 (0.38) | RIPK1TRPV1 | |
| SCHEMBL3914941 | 0.81 | RIPK1 (0.46) | RIPK1RIPK3 | |
| SCHEMBL15565183 | 0.80 | RIPK1 (0.43) | RIPK1TRPV1 | |
| SCHEMBL15565126 | 0.79 | RIPK1 (0.63) | RIPK1 | |
| SCHEMBL19207856 | 0.79 | RIPK1 (0.63) | RIPK1 | |
| SCHEMBL12345900 | 0.78 | ADRA2A (0.38) | — | |
| Hydrochloric Acid SCHEMBL2236148 | 0.77 | ANPEP (0.39) | — | |
| SCHEMBL2235776 | 0.76 | MEN1 (0.37) | RIPK1TRPV1CCKBRCCKAR | |
| SCHEMBL2235041 | 0.74 | METAP1 (0.41) | RIPK1TRPV1CCKBRCCKAR | |
| SCHEMBL2235045 | 0.74 | METAP1 (0.41) | RIPK1TRPV1CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075971-A1 | DERIVATIVES OF 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYL AMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THE SAME | SANOFI-AVENTIS (FR) | 2009-03-19 | — | — | US | disclosed |
| EP-2029555-A2 | DERIVATIVES OF 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYL AMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THE SAME | Sanofi-Aventis (FR) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007135295-A2 | DERIVATIVES OF 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYL AMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THE SAME | SANOFI-AVENTIS (FR) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075971-A1 | DERIVATIVES OF 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYL AMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THE SAME | CYP4B1, AADAC, ALKBH3 | RIPK1 4874/4885TRPV1 1943/4885CCKBR 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.