Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908444 | 0.92 | HTR6 (0.46) | KCNH3CNR2KDM4ETSHRHSD17B10 | |
| SCHEMBL14022904 | 0.91 | ALDH1A1 (0.42) | KCNH3CNR2KDM4ETSHRHSD17B10 | |
| SCHEMBL3918087 | 0.91 | PIM1 (0.40) | KCNH3CNR2KDM4ETSHRHSD17B10 | |
| SCHEMBL3910472 | 0.82 | HTR2A (0.44) | GRM4HTR6HTR1ADRD2HTR2A | |
| SCHEMBL3976997 | 0.81 | HTR6 (0.45) | KCNH3TSHRHTR6HTR1ADRD2 | |
| SCHEMBL3980960 | 0.81 | HTR6 (0.37) | KDRHTR6HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL3911171 | 0.81 | HTR2A (0.44) | KCNH3GRM4HTR6HTR1ADRD2 | |
| SCHEMBL3979528 | 0.74 | HTR6 (0.43) | TSHRHTR6HTR1ADRD2HTR2A | |
| SCHEMBL3918840 | 0.73 | ALDH1A1 (0.48) | KDM4EALDH1A1HTR6HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL3912958 | 0.72 | ALDH1A1 (0.48) | KDM4EALDH1A1HTR6HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928833-B1 | NOVEL QUINOLINE COMPOUNDS CAPABLE OF BINDING AT THE CB2 RECEPTOR | GLAXO GROUP LTD (GB) | 2009-02-18 | — | — | EP | disclosed |
| US-20080249092-A1 | Novel Quinoline Compounds Capable Of Binding At The Cb2 Receptor | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249092-A1 | Novel Quinoline Compounds Capable Of Binding At The Cb2 Receptor | CNR2, CNR1, GPR52 | KCNH3 1098/4885CNR2 1/4885KDM4E 2535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.