Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.45 |
| ▸ | HTR2A | P28223 | 4/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980960 | 0.92 | HTR6 (0.37) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL3979528 | 0.91 | HTR6 (0.43) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL3908444 | 0.89 | HTR6 (0.46) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL3914009 | 0.81 | KCNH3 (0.40) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL3910472 | 0.81 | HTR2A (0.44) | HTR6HTR2AHTR1ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL3911171 | 0.80 | HTR2A (0.44) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL3918087 | 0.80 | PIM1 (0.40) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL14022904 | 0.80 | ALDH1A1 (0.42) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL3918840 | 0.73 | ALDH1A1 (0.48) | HTR6HTR2AHTR1ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL3912958 | 0.72 | ALDH1A1 (0.48) | HTR6HTR2AHTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928833-B1 | NOVEL QUINOLINE COMPOUNDS CAPABLE OF BINDING AT THE CB2 RECEPTOR | GLAXO GROUP LTD (GB) | 2009-02-18 | — | — | EP | claimed |