SCHEMBL391401

SCHEMBL391401

Clc1ccc(C#Cc2c3ccccc3c(C#Cc3ccc(Cl)cc3)c3ccccc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.47
GRM5 P41594 2/20 0.43
APP P05067 1/20 0.42
MAPT P10636 1/20 0.38
ATM Q13315 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
TSHR P16473 1/20 0.38
CYP1A2 P05177 2/20 0.37
CYP2A6 P11509 2/20 0.36
LMNA P02545 2/20 0.36
ADK P55263 1/20 0.36
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
ACACB O00763 1/20 0.33
ASIC3 Q9UHC3 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379887 0.82 APP (0.44) KCNH2GRM5APPMAPTATM
SCHEMBL574585 0.82 APP (0.44) KCNH2GRM5APPMAPTATM
SCHEMBL717633 0.80 APP (0.67) KCNH2GRM5APPMAPTTSHR
SCHEMBL29357652 0.80 APP (0.67) KCNH2GRM5APPMAPTATM
SCHEMBL55761 0.80 APP (0.67) KCNH2GRM5APPMAPTATM
SCHEMBL20015814 0.80 LMNA (0.57) KCNH2GRM5APPMAPTTSHR
SCHEMBL719360 0.80 LMNA (0.57) KCNH2GRM5APPMAPTTSHR
SCHEMBL387788 0.77 APP (0.42) APPMAPTATMTDP1L3MBTL1
SCHEMBL10300070 0.77 APP (0.42) GRM5APPMAPTATMTDP1
Charcoal, Activated SCHEMBL31286310 0.77 KCNH2 (0.54) KCNH2GRM5APPMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090299070-A1 Organic Semiconductors and Their Manufacture CLAP CO., LTD. (KR) 2009-12-03 US claimed
EP-1961052-A1 ORGANIC SEMICONDUCTORS AND THEIR MANUFACTURE Ciba Specialty Chemicals Holding Inc. (CH) 2008-08-27 EP claimed
WO-2007068618-A1 ORGANIC SEMICONDUCTORS AND THEIR MANUFACTURE CIBA HOLDING INC. (CH) 2007-06-21 WO claimed
EP-2573833-A1 Organic semiconductors, their manufacture and semiconductor devices comprising them BASF SE (DE) 2013-03-27 EP disclosed
EP-2573833-A1 Organic semiconductors, their manufacture and semiconductor devices comprising them BASF SE (DE) 2013-03-27 EP disclosed
EP-1961052-B1 ORGANIC SEMICONDUCTORS AND THEIR MANUFACTURE BASF SE (DE) 2013-03-06 EP disclosed
US-8101776-B2 Organic semiconductors and their manufacture BASF SE (DE) 2012-01-24 US disclosed
US-8101776-B2 Organic semiconductors and their manufacture BASF SE (DE) 2012-01-24 US disclosed
US-8101776-B2 Organic semiconductors and their manufacture BASF SE (DE) 2012-01-24 US disclosed
US-20110017981-A1 PROCESS FOR THE PREPARATION OF SEMICONDUCTING LAYERS BASF SE (US) 2011-01-27 US disclosed
EP-2232605-A1 PROCESS FOR THE PREPARATION OF SEMICONDUCTING LAYERS BASF SE (DE) 2010-09-29 EP disclosed
US-20090299070-A1 Organic Semiconductors and Their Manufacture CLAP CO., LTD. (KR) 2009-12-03 US disclosed
US-20090299070-A1 Organic Semiconductors and Their Manufacture CLAP CO., LTD. (KR) 2009-12-03 US disclosed
US-20090299070-A1 Organic Semiconductors and Their Manufacture CLAP CO., LTD. (KR) 2009-12-03 US disclosed
WO-2009077349-A1 PROCESS FOR THE PREPARATION OF SEMICONDUCTING LAYERS BASF SE (DE) 2009-06-25 WO disclosed
WO-2009077349-A1 PROCESS FOR THE PREPARATION OF SEMICONDUCTING LAYERS BASF SE (DE) 2009-06-25 WO disclosed
EP-1961052-A1 ORGANIC SEMICONDUCTORS AND THEIR MANUFACTURE Ciba Specialty Chemicals Holding Inc. (CH) 2008-08-27 EP disclosed
WO-2007068618-A1 ORGANIC SEMICONDUCTORS AND THEIR MANUFACTURE CIBA HOLDING INC. (CH) 2007-06-21 WO disclosed
WO-2007068618-A1 ORGANIC SEMICONDUCTORS AND THEIR MANUFACTURE CIBA HOLDING INC. (CH) 2007-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299070-A1 Organic Semiconductors and Their Manufacture YBX1, CDYL, PROX1 KCNH2 669/4885GRM5 3538/4885APP 2420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.