Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17237437 | 0.88 | SIRT3 (0.51) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL3559657 | 0.78 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL27740539 | 0.77 | KDM4E (0.47) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL29918088 | 0.76 | KDM4C (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL27986525 | 0.75 | CHEK2 (0.45) | KDM4EALDH1A1GAAMAPTTSHR | |
| SCHEMBL946433 | 0.73 | BCAT2 (0.61) | KDM4EALDH1A1MAPTKDM4CSIRT3 | |
| SCHEMBL28042617 | 0.73 | TDP1 (0.52) | KDM4EALDH1A1GAAMAPTKDM4C | |
| SCHEMBL30040297 | 0.72 | SLC22A12 (0.50) | KDM4EALDH1A1GAAMAPTKDM4C | |
| SCHEMBL28168957 | 0.72 | KDM4C (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL1810437 | 0.71 | CYP17A1 (0.57) | KDM4EALDH1A1HPGDHSD17B10CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151311-A1 | NICOTINAMIDE DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2025-07-17 | — | — | WO | disclosed |
| EP-2035386-A1 | ISOQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF CYTOKINE MEDIATED DISEASES | AstraZeneca AB (SE) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007149031-A1 | ISOQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF CYTOKINE MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2007-12-27 | — | — | WO | disclosed |