Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3646839 | 0.80 | PLK4 (0.54) | CHEK2DYRK1ACLK4PLK4MAPK13 | |
| SCHEMBL3559657 | 0.77 | ALDH1A1 (0.54) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL3914464 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL17237437 | 0.77 | SIRT3 (0.51) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL27484628 | 0.76 | ALDH1A1 (0.58) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL23455762 | 0.76 | CDC7 (0.57) | MAPTCHEK2DYRK1ACLK4PLK4 | |
| SCHEMBL2417969 | 0.75 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAMAPTHPGD | |
| SCHEMBL7143112 | 0.74 | PLK4 (0.49) | CHEK2DYRK1ACLK4PLK4MAPK13 | |
| SCHEMBL15567697 | 0.74 | ROCK2 (0.49) | CHEK2DYRK1ACLK4PLK4MAPK13 | |
| SCHEMBL8817729 | 0.74 | PARP1 (0.47) | MAPTCHEK2DYRK1ACLK4PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287707-A | Kinase inhibitors | DEVGEN NV (BE) | 2008-10-15 | — | — | CN | claimed |