Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fluorene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL28987665 | 0.93 | ALDH1A1 (0.40) | ALDH1A1GLATDP1SMN1; SMN2GABRP | |
| Fluorene SCHEMBL154228 | 0.92 | TDP1 (0.47) | ALDH1A1GLATDP1SMN1; SMN2RAB9A | |
| Alcohol SCHEMBL28004110 | 0.87 | PNMT (0.38) | ALDH1A1GLATDP1RAB9ANPC1 | |
| Fluorene SCHEMBL27831385 | 0.86 | TDP1 (0.44) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| Fluorene SCHEMBL919560 | 0.86 | TDP1 (0.44) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| Fluorene SCHEMBL27748981 | 0.86 | ALDH1A1 (0.42) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| Fluorene SCHEMBL22588161 | 0.86 | TDP1 (0.46) | ALDH1A1GLATDP1SMN1; SMN2TSHR | |
| Fluorene SCHEMBL28074268 | 0.85 | ALDH1A1 (0.44) | ALDH1A1GLATDP1SMN1; SMN2GABRP | |
| 2-Phenylphenol SCHEMBL28050949 | 0.84 | ALDH1A1 (0.46) | ALDH1A1GLATDP1MGLL | |
| Fluorene SCHEMBL27885461 | 0.83 | TRPA1 (0.45) | ALDH1A1GLATDP1SMN1; SMN2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2105775-A2 | Apparatus using a double layered waveguide structure , optical touch panel based on such a waveguide, and method of fabricating such a waveguide | Nitto Denko Corporation (JP) | 2009-09-30 | — | — | EP | claimed |
| US-20090237375-A1 | APPARATUS USING WAVEGUIDE, OPTICAL TOUCH PANEL, AND METHOD OF FABRICATING WAVEGUIDE | NITTO DENKO CORPORATION (JP) | 2009-09-24 | — | — | US | claimed |
| CN-115485593-A | Polarizing plate and polarizing plate with optical function layer | 日东电工株式会社 | 2022-12-16 | — | — | CN | disclosed |
| US-10606002-B2 | Opto-electric hybrid board and manufacturing method for same | NITTO DENKO CORPORATION (JP) | 2020-03-31 | — | — | US | disclosed |
| EP-3312224-B1 | POLYAMIDE MOULDING COMPOSITION AND MULTI-LAYERED STRUCTURE MADE HEREFROM | EMS PATENT AG (CH) | 2018-12-26 | — | — | EP | disclosed |
| EP-3312224-A1 | POLYAMIDE MOULDING COMPOSITION AND MULTI-LAYERED STRUCTURE MADE HEREFROM | EMS-PATENT AG (CH) | 2018-04-25 | — | — | EP | disclosed |
| US-9828469-B2 | Polyimide precursor, polyimide resin film produced from said polyimide precursor, display element, optical element, light-receiving element, touch panel and circuit board each equipped with said polyimide resin film, organic EL display, and methods respectively for producing organic EL element and color filter | TORAY INDUSTRIES, INC. (JP) | 2017-11-28 | — | — | US | disclosed |
| US-20170299823-A1 | OPTO-ELECTRIC HYBRID BOARD AND MANUFACTURING METHOD FOR SAME | NITTO DENKO CORPORATION (JP) | 2017-10-19 | — | — | US | disclosed |
| US-20160222165-A1 | POLYIMIDE PRECURSOR, POLYIMIDE RESIN FILM PRODUCED FROM SAID POLYIMIDE PRECURSOR, DISPLAY ELEMENT, OPTICAL ELEMENT, LIGHT-RECEIVING ELEMENT, TOUCH PANEL AND CIRCUIT BOARD EACH EQUIPPED WITH SAID POLYIMIDE RESIN FILM, ORGANIC EL DISPLAY, AND METHODS RESPECTIVELY FOR PRODUCING ORGANIC EL ELEMENT AND COLOR FILTER | TORAY INDUSTRIES, INC. (JP) | 2016-08-04 | — | — | US | disclosed |
| US-9297958-B2 | Opto-electric hybrid board and method of manufacturing same | NITTO DENKO CORPORATION (JP) | 2016-03-29 | — | — | US | disclosed |
| US-20140306209-A1 | ORGANIC EL DEVICE AND METHOD FOR PRODUCING THE SAME | NITTO DENKO CORPORATION (JP) | 2014-10-16 | — | — | US | disclosed |
| EP-2736309-A1 | Opto-electric hybrid board and method of manufacturing same | NITTO DENKO CORPORATION (JP) | 2014-05-28 | — | — | EP | disclosed |
| US-8200051-B2 | Apparatus using waveguide, optical touch panel, and method of fabricating waveguide | NITTO DENKO CORPORATION (JP) | 2012-06-12 | — | — | US | disclosed |
| EP-2105775-A2 | Apparatus using a double layered waveguide structure , optical touch panel based on such a waveguide, and method of fabricating such a waveguide | Nitto Denko Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |
| CN-101546239-A | Apparatus using waveguide, optical touch panel, and method of fabricating waveguide | NITTO DENKO CORP | 2009-09-30 | — | — | CN | disclosed |
| US-20090237375-A1 | APPARATUS USING WAVEGUIDE, OPTICAL TOUCH PANEL, AND METHOD OF FABRICATING WAVEGUIDE | NITTO DENKO CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-20090039545-A1 | SEALING STRUCTURE OF TERMINAL AND SEALING MATERIAL THEREFOR | OMRON CORPORATION (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-2023174-A1 | Optical waveguide device and manufacturing method thereof | Nitto Denko Corporation (JP) | 2009-02-11 | — | — | EP | disclosed |
| US-20050072591-A1 | Sealing structure of terminal and sealing material therefor | OMRON CORPORATION (JP) | 2005-04-07 | — | — | US | disclosed |
| EP-1484781-A2 | Sealing structure and sealing material therefor | Omron Corporation (JP) | 2004-12-08 | — | — | EP | disclosed |