SCHEMBL3915468

SCHEMBL3915468

CS(=O)(=O)c1ccc(Oc2ccc(S(=O)(=O)N3CCN(C(=O)N4CCOCC4)CC3C(=O)NO)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 18/20 0.80
MMP3 P08254 17/20 0.80
MMP13 P45452 15/20 0.80
MMP7 P09237 14/20 0.80
MMP9 P14780 13/20 0.80
MMP2 P08253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778961 0.90 MMP1 (0.77) MMP1MMP3MMP13MMP7MMP9
SCHEMBL3915571 0.84 MMP1 (0.78) MMP1MMP3MMP13MMP7MMP9
SCHEMBL3942611 0.83 MMP13 (0.77) MMP1MMP3MMP13MMP7MMP9
SCHEMBL779078 0.81 MMP1 (0.66) MMP1MMP3MMP13MMP7MMP9
SCHEMBL778717 0.81 MMP1 (0.66) MMP1MMP3MMP13MMP7MMP9
SCHEMBL3917439 0.80 MMP1 (0.81) MMP1MMP3MMP13MMP7MMP9
SCHEMBL778952 0.80 MMP1 (0.64) MMP1MMP3MMP13MMP7MMP9
SCHEMBL778890 0.79 MMP1 (0.64) MMP1MMP3MMP13MMP7MMP9
SCHEMBL14878463 0.78 MMP1 (0.60) MMP1MMP3MMP13MMP7MMP9
SCHEMBL779025 0.78 MMP1 (0.61) MMP1MMP3MMP13MMP7MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7504537-B2 Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2009-03-17 US disclosed
US-7504537-B2 Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2009-03-17 US disclosed
US-7504537-B2 Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2009-03-17 US disclosed
US-20050282905-A1 Hydroxamic acid derivative and mmp inhibitor containing the same as active ingredient DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2005-12-22 US disclosed
EP-1466899-A1 HYDROXAMIC ACID DERIVATIVE AND MMP INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 2004-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282905-A1 Hydroxamic acid derivative and mmp inhibitor containing the same as active ingredient MMP13, MMP3, MMP2 MMP1 11/4885MMP3 2/4885MMP13 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.