Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.47 |
| ▸ | ADH1C | P00326 | 2/20 | 0.47 |
| ▸ | ADH1A | P07327 | 2/20 | 0.47 |
| ▸ | ADH4 | P08319 | 2/20 | 0.47 |
| ▸ | ADH7 | P40394 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29380868 | 1.00 | ADH1B (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL29380140 | 1.00 | ADH1B (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL29380352 | 1.00 | ADH1B (0.47) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL11144441 | 0.98 | — | — | |
| SCHEMBL28553161 | 0.90 | — | — | |
| SCHEMBL14601128 | 0.84 | TSHR (0.31) | TSHRSMN1; SMN2 | |
| SCHEMBL5326446 | 0.79 | — | — | |
| SCHEMBL7871168 | 0.78 | GPR84 (0.41) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL7863831 | 0.78 | GPR84 (0.41) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL17879364 | 0.76 | TSHR (0.50) | TSHRMAPTGPR84FDPSFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019964-A2 | METHODS AND COMPOUNDS TO MODULATE PARVOVIRUS TRANSDUCTION OF MAMMALIAN CELLS OR TO ALTER VIRUS INFECTION. METHOD TO IDENTIFY A VIRAL RECEPTOR OR CO-RECEPTOR | University of Iowa Research Foundation (US) | 2009-02-04 | — | — | EP | disclosed |
| US-20090017062-A1 | Methods and compounds to alter virus infection | IOWA RESEARCH FOUNDATION IOWA CENTERS FOR ENTERPRI (US) | 2009-01-15 | — | — | US | disclosed |
| US-20080261201-A1 | Methods and compounds to alter virus infection | UNIVERSITY OF IOWA RESEARCH FOUNDATION IOWA CENTERS FOR ENTERPRISE (US) | 2008-10-23 | — | — | US | disclosed |
| WO-2007127464-A2 | METHODS AND COMPOUNDS TO MODULATE PARVOVIRUS TRANSDUCTION OF MAMMALIAN CELLS OR TO ALTER VIRUS INFECTION, METHOD TO IDENTIFY A VIRAL RECEPTOR OR CO-RECEPTOR | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20060008512-A1 | Composition and methods for improved animal performance | HOOGE DANNY M | 2006-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017062-A1 | Methods and compounds to alter virus infection | CYBB, NOX4, NOX5 | ADH1B 65/4885ADH1C 1330/4885ADH1A 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.