Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916132 | 1.00 | FBP1 (0.39) | FBP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL3594422 | 0.81 | RPS6KA3 (0.45) | FBP1RPS6KA3JAK3KIF11NFE2L2 | |
| SCHEMBL3594419 | 0.81 | RPS6KA3 (0.45) | FBP1RPS6KA3JAK3KIF11NFE2L2 | |
| SCHEMBL29656448 | 0.78 | ALDH1A1 (0.44) | FBP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL3508781 | 0.78 | ALDH1A1 (0.44) | FBP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL3921456 | 0.77 | VCAM1 (0.41) | FBP1ALDH1A1TSHRTDP1VCAM1 | |
| SCHEMBL3921458 | 0.77 | VCAM1 (0.41) | FBP1ALDH1A1TSHRTDP1VCAM1 | |
| SCHEMBL16954679 | 0.76 | TSHR (0.43) | FBP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL15542721 | 0.76 | TSHR (0.43) | FBP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL16961890 | 0.76 | ALDH1A1 (0.43) | FBP1ALDH1A1CYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209552-A1 | Organic Compounds | NOVARTIS AG | 2009-08-20 | — | — | US | disclosed |
| EP-2032555-A1 | PYRROLE DERIVATIVES WITH CRTH2 RECEPTOR MODULATOR ACTIVITY | Novartis AG (CH) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007144127-A1 | PYRROLE DERIVATIVES WITH CRTH2 RECEPTOR MODULATOR ACTIVITY | NOVARTIS AG (CH) | 2007-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209552-A1 | Organic Compounds | SLCO1B3, SLCO1B1, SLC10A6 | FBP1 2862/4885ALDH1A1 439/4885CYP3A4 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.