SCHEMBL3916137

SCHEMBL3916137

[SiH3]O[SiH2]C=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.44
TRPA1 O75762 3/20 0.39
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
NFE2L2 Q16236 2/20 0.38
CYP19A1 P11511 1/20 0.38
MAOA P21397 1/20 0.38
ALOX5 P09917 1/20 0.38
MAPK1 P28482 1/20 0.38
IDO1 P14902 2/20 0.38
HDAC3 O15379 1/20 0.37
TNKS O95271 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL6572091 0.83 GLA (0.43) MAOBALDH1A1LMNAHDAC3TNKS
SCHEMBL8990017 0.81 MAOB (0.48) MAOBTRPA1ALDH1A1LMNANFE2L2
SCHEMBL2367510 0.81 MAOB (0.40) MAOBTRPA1ALDH1A1LMNANFE2L2
SCHEMBL1468386 0.77 TRPA1 (0.48) MAOBTRPA1ALDH1A1NFE2L2CYP1A2
SCHEMBL1468384 0.77 TRPA1 (0.48) MAOBTRPA1ALDH1A1NFE2L2CYP1A2
(Z)-1,2-Diphenylethene SCHEMBL3792039 0.75 MAOB (0.58) MAOBTRPA1NFE2L2CYP19A1MAOA
(Z)-1,2-Diphenylethene SCHEMBL3792042 0.75 MAOB (0.58) MAOBTRPA1NFE2L2CYP19A1MAOA
SCHEMBL3372078 0.74 TRPA1 (0.45) MAOBTRPA1NFE2L2CYP19A1MAOA
SCHEMBL9578541 0.74 GLA (0.50) MAOBALDH1A1LMNAHDAC3TNKS
SCHEMBL8072802 0.73 MAOB (0.50) MAOBTRPA1ALDH1A1LMNANFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119730144-A Liquid metal sandwich type heat-conducting gel sheet and preparation method thereof 西部宝德科技股份有限公司 2025-03-28 CN claimed
CN-111410459-B Bi-component heat-conducting gel for 5G communication and preparation method thereof 深圳市博恩实业有限公司 2022-05-27 CN claimed
US-7322694-B2 Hybrid contact lens system and method SYNERGEYES, INC. (US) 2008-01-29 US claimed
EP-1714182-A2 HYBRID CONTACT LENS SYSTEM AND METHOD Quarter Lambda Technologies Inc. (US) 2006-10-25 EP claimed
WO-2005079290-A2 HYBRID CONTACT LENS SYSTEM AND METHOD SYNERGEYES, INC. (US) 2005-09-01 WO claimed
US-20050018130-A1 Hybrid contact lens system and method SYNERGEYES, INC. 2005-01-27 US claimed
JP-56028604-A None JP disclosed
EP-4043508-B9 SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF JOHNSON & JOHNSON VISION CARE (US) 2025-10-08 EP disclosed
EP-4043508-B1 SILICONE HYDROGELS COMPRISING N-ALKYL METHACRYLAMIDES AND CONTACT LENSES MADE THEREOF JOHNSON & JOHNSON VISION CARE (US) 2025-04-09 EP disclosed
CN-119730144-A Liquid metal sandwich type heat-conducting gel sheet and preparation method thereof 西部宝德科技股份有限公司 2025-03-28 CN disclosed
WO-2024084190-A1 ORTHOKERATOLOGY CONTACT LENSES AND RELATED METHODS COOPERVISION INTERNATIONAL LIMITED (GB) 2024-04-25 WO disclosed
CN-117659661-A Organosilicon copolymer modified polycarbonate and preparation process thereof 东莞市百富塑料科技有限公司 2024-03-08 CN disclosed
CN-116285678-B Preparation method of nano modified styrene-acrylic-siloxane graft copolymer composite emulsion 青岛理工大学 2023-12-19 CN disclosed
EP-0505997-B1 Process for producing styrenic polymer and copolymer IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5378777-A Styrene monomer substituted with silicon group, transition metal complex catalyst IDEMITSU KOSAN CO., LTD. (JP) 1995-01-03 US disclosed
EP-0505997-A2 Process for producing styrenic polymer and copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
US-4644041-A Preparation of poly(methylmethacrylate) polymer particles THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) 1987-02-17 US disclosed
US-4550139-A OPTICALLY CLEAR LENS WITH IMPROVED OXYGEN PERMEABILITY PETRARCH SYSTEMS, INC. (US) 1985-10-29 US disclosed
US-4550139-A OPTICALLY CLEAR LENS WITH IMPROVED OXYGEN PERMEABILITY PETRARCH SYSTEMS, INC. (US) 1985-10-29 US disclosed
JP-S5628604-A SELECTIVE GAS PERMEABLE MEMBRANE MATSUSHITA ELECTRIC IND CO LTD 1981-03-20 JP disclosed