SCHEMBL2367510

SCHEMBL2367510

[SiH3]O[SiH2]O[SiH2]O[SiH2]C=Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.40
TRPA1 O75762 2/20 0.36
MAPK1 P28482 2/20 0.35
NFE2L2 Q16236 1/20 0.35
CYP19A1 P11511 1/20 0.35
MAOA P21397 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
ALOX5 P09917 1/20 0.35
RELA Q04206 3/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP1B1 Q16678 1/20 0.33
GRIN2D O15399 2/20 0.32
GRIN3B O60391 2/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2A Q12879 2/20 0.32
GRIN2B Q13224 2/20 0.32
GRIN2C Q14957 2/20 0.32
GRIN3A Q8TCU5 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3916137 0.81 MAOB (0.44) MAOBTRPA1MAPK1NFE2L2CYP19A1
SCHEMBL8990017 0.80 MAOB (0.48) MAOBTRPA1MAPK1NFE2L2CYP19A1
SCHEMBL6657189 0.78 TRPA1 (0.37) MAOBTRPA1MAPK1NFE2L2CYP19A1
SCHEMBL3372078 0.73 TRPA1 (0.45) MAOBTRPA1NFE2L2CYP19A1MAOA
Biphenyl SCHEMBL27732120 0.69 ALDH1A1 (0.47) MAPK1MAOAALDH1A1RELACYP1A2
SCHEMBL1468386 0.69 TRPA1 (0.48) MAOBTRPA1NFE2L2ALDH1A1RELA
SCHEMBL1468384 0.69 TRPA1 (0.48) MAOBTRPA1NFE2L2ALDH1A1RELA
SCHEMBL2367163 0.68 ALDH1A1 (0.37) ALDH1A1MAPTRECQL
(Z)-1,2-Diphenylethene SCHEMBL3792039 0.66 MAOB (0.58) MAOBTRPA1NFE2L2CYP19A1MAOA
(Z)-1,2-Diphenylethene SCHEMBL3792042 0.66 MAOB (0.58) MAOBTRPA1NFE2L2CYP19A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160028090-A1 CATHODE FOR FUEL CELL TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2016-01-28 US disclosed
EP-2978057-A1 CATHODE FOR FUEL CELL Toyota Jidosha Kabushiki Kaisha (JP) 2016-01-27 EP disclosed
US-8288496-B2 Contact lens and its manufacturing method NIPPON CONTACT LENS INC. (JP) 2012-10-16 US disclosed
US-20110237701-A1 CONTACT LENS AND ITS MANUFACTURING METHOD NIPPON CONTACT LENS INC. (JP) 2011-09-29 US disclosed
EP-2369370-A2 Contact lens and its manufacturing method Nippon Contact Lens Inc. (JP) 2011-09-28 EP disclosed