Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CHAT | P28329 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990017 | 0.87 | MAOB (0.48) | TRPA1RELAMAOBNFE2L2CYP19A1 | |
| SCHEMBL1468384 | 0.78 | TRPA1 (0.48) | TRPA1RELAMAOBNFE2L2CYP1A1 | |
| SCHEMBL1468386 | 0.78 | TRPA1 (0.48) | TRPA1RELAMAOBNFE2L2CYP1A1 | |
| SCHEMBL355020 | 0.75 | MAOB (0.50) | TRPA1RELAMAOBNFE2L2CYP19A1 | |
| SCHEMBL3916137 | 0.74 | MAOB (0.44) | TRPA1RELAMAOBNFE2L2CYP19A1 | |
| SCHEMBL5472329 | 0.73 | TRPA1 (0.39) | TRPA1RELAMAOBNFE2L2ALOX15 | |
| SCHEMBL17239119 | 0.73 | HTR2A (0.40) | TRPA1MAOBALOX15CHATTDP1 | |
| SCHEMBL708911 | 0.73 | TRPA1 (0.39) | TRPA1RELAMAOBNFE2L2CYP19A1 | |
| SCHEMBL1470879 | 0.73 | RELA (0.48) | TRPA1RELAMAOBMAOACYP1A2 | |
| SCHEMBL27722650 | 0.73 | TRPA1 (0.39) | TRPA1RELAMAOBNFE2L2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750157-B1 | CONTACT LENS | MENICON CO LTD (JP) | 2010-10-13 | — | — | EP | disclosed |
| US-20090247662-A1 | Contact Lens Material | MATSUMOTO MASAHIRO | 2009-10-01 | — | — | US | disclosed |
| EP-1750157-A1 | CONTACT LENS | MENICON CO., LTD. (JP) | 2007-02-07 | — | — | EP | disclosed |
| EP-1696257-A1 | CONTACT LENS MATERIAL | MENICON CO., LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |