Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 11/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 9/20 | 0.52 |
| ▸ | TUBB | P07437 | 9/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 9/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 9/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 9/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 9/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 9/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 9/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 9/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 9/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 9/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 9/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 9/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916595 | 0.89 | TUBB1 (0.62) | TUBB1PTGS1PTGS2TUBB4ATUBB | |
| SCHEMBL3917866 | 0.86 | PTGS1 (0.53) | TUBB1PTGS1PTGS2TUBB4ATUBB | |
| SCHEMBL3918345 | 0.84 | TUBB4A (0.59) | TUBB1PTGS1PTGS2TUBB4ATUBB | |
| SCHEMBL3915711 | 0.78 | TUBB1 (0.48) | TUBB1PTGS1PTGS2TUBB4ATUBB | |
| SCHEMBL1562262 | 0.76 | TUBB1 (1.00) | TUBB1PTGS1PTGS2TUBB4ATUBB | |
| SCHEMBL31004957 | 0.75 | TUBB1 (0.76) | TUBB1PTGS1PTGS2TUBB4ATUBB | |
| SCHEMBL3916999 | 0.74 | PTGS1 (0.50) | TUBB1PTGS1PTGS2TUBB4ATUBB | |
| SCHEMBL31498186 | 0.73 | KDM4E (0.59) | TUBB1PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL5196745 | 0.73 | KDM4E (0.59) | TUBB1PTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL3917889 | 0.71 | TUBB1 (0.49) | TUBB1PTGS1PTGS2TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | claimed |
| US-20050267108-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-12-01 | — | — | US | claimed |
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | disclosed |
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | disclosed |
| US-20050267108-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267108-A1 | Indole compounds | TUBB1, TUBB3, TUBB | TUBB1 1/4885PTGS1 652/4885PTGS2 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.