Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 13/20 | 0.59 |
| ▸ | TUBB | P07437 | 13/20 | 0.59 |
| ▸ | TUBA3C | P0DPH7 | 13/20 | 0.59 |
| ▸ | TUBA1B | P68363 | 13/20 | 0.59 |
| ▸ | TUBA4A | P68366 | 13/20 | 0.59 |
| ▸ | TUBB4B | P68371 | 13/20 | 0.59 |
| ▸ | TUBB3 | Q13509 | 13/20 | 0.59 |
| ▸ | TUBB2A | Q13885 | 13/20 | 0.59 |
| ▸ | TUBB8 | Q3ZCM7 | 13/20 | 0.59 |
| ▸ | TUBA3E | Q6PEY2 | 13/20 | 0.59 |
| ▸ | TUBA1A | Q71U36 | 13/20 | 0.59 |
| ▸ | TUBA1C | Q9BQE3 | 13/20 | 0.59 |
| ▸ | TUBB6 | Q9BUF5 | 13/20 | 0.59 |
| ▸ | TUBB2B | Q9BVA1 | 13/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 13/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3916595 | 0.84 | TUBB1 (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3916211 | 0.84 | TUBB1 (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3917866 | 0.82 | PTGS1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3915711 | 0.82 | TUBB1 (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3916999 | 0.81 | PTGS1 (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31744857 | 0.81 | ALDH1A1 (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL670200 | 0.81 | AHR (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3917889 | 0.78 | TUBB1 (0.49) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31744776 | 0.74 | PTGS2 (0.48) | MAPTALDH1A1KDM4ENPSR1MEN1 | |
| SCHEMBL28281488 | 0.71 | MAPT (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | claimed |
| US-20050267108-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-12-01 | — | — | US | claimed |
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | disclosed |
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | disclosed |
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | disclosed |
| US-20050267108-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267108-A1 | Indole compounds | TUBB1, TUBB3, TUBB | TUBB4A 7/4885TUBB 3/4885TUBA3C 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.