Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135460 | 0.97 | ACHE (0.42) | ACHETDP1CA1CA2CA7 | |
| SCHEMBL137128 | 0.95 | ACHE (0.40) | ACHETDP1CA1CA2CA7 | |
| SCHEMBL13088184 | 0.72 | CA1 (0.33) | ACHECA1CA2CA7CA9 | |
| SCHEMBL107172 | 0.72 | ALDH1A1 (0.42) | ACHECA1CA2CA9ALDH1A1 | |
| SCHEMBL12257147 | 0.71 | HPGD (0.38) | ALDH1A1NISCH | |
| Bromide SCHEMBL11632896 | 0.70 | IDO1 (0.32) | — | |
| SCHEMBL133003 | 0.70 | ALDH1A1 (0.40) | ACHECA1CA2CA9ALDH1A1 | |
| SCHEMBL4569613 | 0.70 | CA1 (0.48) | ACHETDP1CA1CA2CA7 | |
| P-Xylene SCHEMBL28317794 | 0.67 | ACHE (0.73) | ACHETDP1CA1CA2CA7 | |
| P-Xylene SCHEMBL28063776 | 0.67 | ACHE (0.73) | ACHETDP1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7527913-B2 | Photoacid generators, photoresist composition including the same and method of forming pattern using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-05-05 | — | — | US | disclosed |
| US-20080182203-A1 | Photoacid generators, photoresist composition including the same and method of forming pattern using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182203-A1 | Photoacid generators, photoresist composition including the same and method of forming pattern using the same | SUN2, ASIC1, STOM | ACHE 4426/4885TDP1 3444/4885CA1 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.