SCHEMBL3917019

SCHEMBL3917019

CSc1c(O)cccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.45
HPGD P15428 5/20 0.45
HSD17B10 Q99714 5/20 0.45
LMNA P02545 4/20 0.45
ALDH1A1 P00352 4/20 0.45
CA2 P00918 4/20 0.45
RECQL P46063 3/20 0.45
TDP1 Q9NUW8 3/20 0.45
CA1 P00915 3/20 0.45
EGFR P00533 2/20 0.45
FYN P06241 2/20 0.45
MMP9 P14780 2/20 0.45
ADAMTS4 O75173 1/20 0.45
MMP2 P08253 1/20 0.45
MMP8 P22894 1/20 0.45
CA6 P23280 1/20 0.45
CDK2 P24941 1/20 0.45
MMP12 P39900 1/20 0.45
ADAMTS5 Q9UNA0 1/20 0.45
MAPT P10636 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9810705 0.85 ALOX15 (0.38) ALOX15HPGDHSD17B10LMNAALDH1A1
SCHEMBL11605537 0.85 TRPA1 (0.52) ALOX15HPGDHSD17B10LMNAALDH1A1
SCHEMBL23685905 0.83 ALOX15 (0.36) ALOX15HPGDHSD17B10LMNAALDH1A1
SCHEMBL24448464 0.83 TSHR (0.50) ALOX15HPGDHSD17B10LMNAALDH1A1
SCHEMBL15934305 0.79 GAA (0.40) ALOX15HPGDHSD17B10LMNAALDH1A1
SCHEMBL6553879 0.79 ALOX15 (0.33) ALOX15HPGDHSD17B10LMNAALDH1A1
SCHEMBL15934246 0.79 IDO1 (0.39) ALOX15HPGDHSD17B10LMNAALDH1A1
SCHEMBL29951357 0.78 ERN1 (0.55) LMNAALDH1A1CA2TDP1CA1
SCHEMBL22529091 0.76 KDM4E (0.55) ALOX15HPGDHSD17B10LMNAALDH1A1
SCHEMBL8888927 0.75 ALDH1A1 (0.50) ALOX15HPGDHSD17B10LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357507-A1 SULFUR-CONTAINING POLYMER, METHOD FOR PRODUCING SAME, AND SULFUR-CONTAINING POLYMER COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 2023-11-09 US disclosed
WO-2021065619-A1 POLISHING PAD AND METHOD FOR MANUFACTURING POLISHED PRODUCT 富士紡ホールディングス株式会社 2021-04-08 WO disclosed
US-8084448-B2 Organic compounds NOVARTIS AG (CH) 2011-12-27 US disclosed
US-20090181928-A1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2009-07-16 US disclosed
EP-2038267-A2 THIADIAZOLIDINONE INHIBITORS OF PTPASE Novartis AG (CH) 2009-03-25 EP disclosed
WO-2007115058-A2 THIADIAZOLIDINONE INHIBITORS OF PTPASE NOVARTIS AG (CH) 2007-10-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181928-A1 ORGANIC COMPOUNDS PTPRS, PTPRO, PTPRC ALOX15 280/4885HPGD 2515/4885HSD17B10 794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.