Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810705 | 0.85 | ALOX15 (0.38) | ALOX15LMNAHPGDHSD17B10MAPT | |
| SCHEMBL3917019 | 0.79 | ALOX15 (0.45) | ALOX15LMNAHPGDHSD17B10MAPT | |
| SCHEMBL11605537 | 0.71 | TRPA1 (0.52) | ALOX15LMNAHPGDHSD17B10MAPT | |
| SCHEMBL24448464 | 0.70 | TSHR (0.50) | ALOX15LMNAHPGDHSD17B10MAPT | |
| SCHEMBL6553868 | 0.70 | HSD17B10 (0.36) | ALOX15LMNAHPGDHSD17B10MAPT | |
| SCHEMBL23685905 | 0.70 | ALOX15 (0.36) | ALOX15LMNAHPGDHSD17B10MAPT | |
| SCHEMBL31550782 | 0.69 | ALDH1A1 (0.52) | ALOX15LMNAHPGDHSD17B10MAPT | |
| SCHEMBL2834212 | 0.69 | ALDH1A1 (0.52) | ALOX15LMNAHPGDHSD17B10MAPT | |
| SCHEMBL337809 | 0.67 | — | — | |
| SCHEMBL29368735 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732928-B1 | METHOD OF LOWERING SERUM CHOLESTEROL LEVELS WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS | MERRELL PHARMA INC (US) | 2004-12-22 | — | — | EP | claimed |