Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 18/20 | 0.81 |
| ▸ | TUBB | P07437 | 18/20 | 0.81 |
| ▸ | TUBA3C | P0DPH7 | 18/20 | 0.81 |
| ▸ | TUBA1B | P68363 | 18/20 | 0.81 |
| ▸ | TUBA4A | P68366 | 18/20 | 0.81 |
| ▸ | TUBB4B | P68371 | 18/20 | 0.81 |
| ▸ | TUBB3 | Q13509 | 18/20 | 0.81 |
| ▸ | TUBB2A | Q13885 | 18/20 | 0.81 |
| ▸ | TUBB8 | Q3ZCM7 | 18/20 | 0.81 |
| ▸ | TUBA3E | Q6PEY2 | 18/20 | 0.81 |
| ▸ | TUBA1A | Q71U36 | 18/20 | 0.81 |
| ▸ | TUBA1C | Q9BQE3 | 18/20 | 0.81 |
| ▸ | TUBB6 | Q9BUF5 | 18/20 | 0.81 |
| ▸ | TUBB2B | Q9BVA1 | 18/20 | 0.81 |
| ▸ | TUBB1 | Q9H4B7 | 18/20 | 0.81 |
| ▸ | IDO1 | P14902 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6108183 | 0.84 | IDO1 (0.66) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2552819 | 0.83 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6109298 | 0.81 | IDO1 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5811628 | 0.79 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5807181 | 0.77 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5808034 | 0.77 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5809417 | 0.77 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5812276 | 0.77 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5812015 | 0.77 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5811687 | 0.77 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | claimed |
| US-20050267108-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-12-01 | — | — | US | claimed |
| US-6933316-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-08-23 | — | — | US | claimed |
| EP-1506960-A1 | Indole compounds as inhibitors of tubulin polymerisation for the treatment of angiogenesis-related disorders | National Health Research Institutes (TW) | 2005-02-16 | — | — | EP | claimed |
| US-20030195244-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2003-10-16 | — | — | US | claimed |
| US-7632955-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-12-15 | — | — | US | disclosed |
| US-7632955-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-12-15 | — | — | US | disclosed |
| US-7632955-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-12-15 | — | — | US | disclosed |
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | disclosed |
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | disclosed |
| US-7528165-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-05-05 | — | — | US | disclosed |
| US-20050267108-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-12-01 | — | — | US | disclosed |
| US-20050267194-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-12-01 | — | — | US | disclosed |
| US-6933316-B2 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2005-08-23 | — | — | US | disclosed |
| US-6924284-B2 | PARP inhibitors | ICOS CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |
| EP-1506960-A1 | Indole compounds as inhibitors of tubulin polymerisation for the treatment of angiogenesis-related disorders | National Health Research Institutes (TW) | 2005-02-16 | — | — | EP | disclosed |
| US-20030195244-A1 | Indole compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267108-A1 | Indole compounds | TUBB1, TUBB3, TUBB | TUBB4A 7/4885TUBB 3/4885TUBA3C 18/4885 |
| US-20050267194-A1 | Indole compounds | TUBB1, TUBB, TUBB3 | TUBB4A 7/4885TUBB 2/4885TUBA3C 22/4885 |
| US-20030195244-A1 | Indole compounds | NR2C2, NPSR1, HCRTR2 | TUBB4A 1828/4885TUBB 829/4885TUBA3C 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.