Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917099 | 0.90 | ALDH1A1 (0.51) | HRH3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3918357 | 0.86 | LMNA (0.55) | HRH3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1393985 | 0.82 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL1394606 | 0.82 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL1393987 | 0.82 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL3916728 | 0.82 | HRH3 (0.71) | HRH3MEN1KMT2AGAAATM | |
| SCHEMBL3915931 | 0.81 | HRH3 (0.44) | HRH3ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3311684 | 0.81 | HRH3 (0.64) | HRH3MEN1KMT2AGAAHDAC6 | |
| Hydrochloric Acid SCHEMBL1394710 | 0.81 | KMT2A (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL1394707 | 0.81 | KMT2A (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038253-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | Arrow Therapeutics Limited (GB) | 2009-03-25 | — | — | EP | disclosed |
| WO-2007138242-A1 | BIPHENYL DERIVATIVES AND THEIR USE IN TREATING HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2007-12-06 | — | — | WO | disclosed |