SCHEMBL3919098

SCHEMBL3919098

CO[SiH](OC)C(C)CCOC(=O)c1ccccn1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 1/20 0.49
▸ PKM P14618 1/20 0.48
▸ ALDH1A1 P00352 7/20 0.43
▸ L3MBTL1 Q9Y468 5/20 0.43
▸ KDM4E B2RXH2 2/20 0.43
▸ GAA P10253 1/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ MAPT P10636 1/20 0.42
▸ KMT2A Q03164 3/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ ALOX15 P16050 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3908859 0.87 APP (0.47) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL3912354 0.86 PKM (0.50) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL23661943 0.83 APP (0.56) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL3919109 0.80 CYP19A1 (0.42) ALDH1A1KMT2AMEN1NPC1HSD17B10
SCHEMBL6267530 0.79 LMNA (0.54) PKMALDH1A1KDM4EGAAKMT2A
SCHEMBL3915865 0.77 KMT2A (0.52) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL3918077 0.77 CYP19A1 (0.43) PKMALDH1A1L3MBTL1KDM4EGAA
SCHEMBL31313628 0.76 APP (0.57) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL29067688 0.76 APP (0.57) APPPKMALDH1A1L3MBTL1KDM4E
SCHEMBL10458604 0.76 APP (0.57) APPPKMALDH1A1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 — — US disclosed
EP-1840158-B1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2009-02-18 — — EP disclosed
EP-1840158-A1 METHOD FOR VULCANIZATION AND ADHESION OF RUBBER COMPOSITION WITH ARTICLE TO BE ADHERED BEING MADE OF BRASS OR PLATED WITH BRASS, REINFORCING MATERIAL FOR RUBBER ARTICLE, RUBBER-REINFORCING MATERIAL COMPOSITE, AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-10-03 — — EP disclosed
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