Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231071 | 0.98 | KAT6A (0.46) | KAT6AMYCTSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL30476135 | 0.98 | KAT6A (0.46) | KAT6AMYCTSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL8378084 | 0.95 | KAT6A (0.44) | KAT6AMYCTSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL8380966 | 0.95 | KAT6A (0.44) | KAT6AMYCTSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL8376433 | 0.95 | KAT6A (0.44) | KAT6AMYCTSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL8378097 | 0.95 | KAT6A (0.44) | KAT6AMYCTSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL8376452 | 0.95 | KAT6A (0.44) | KAT6AMYCTSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL8379692 | 0.95 | NFE2L2 (0.44) | KAT6AMYCTSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL8379463 | 0.95 | KAT6A (0.44) | KAT6AMYCTSHRSMN1; SMN2HSD11B1 | |
| SCHEMBL8381980 | 0.95 | KAT6A (0.44) | KAT6AMYCTSHRSMN1; SMN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658552-B1 | Process for the preparation of alpha-tocopherol derivatives | EISAI CO LTD (JP) | 1999-03-31 | — | — | EP | claimed |
| US-5532387-A | CYCLIZATION OF TRIMETHYLHYDROQUINONE AND AN ALKENYL ALCOHOL, REUSABLE CATALYST, IIIB FLUOROSULFONATE, NITRATE, SULFATE, OR FLUOROALKYLSULFONATE | EISAI CO., LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| CN-1108254-A | Process for the preparation of alpha-tocopherol derivatives | EISAI CO LTD (JP) | 1995-09-13 | — | — | CN | claimed |
| EP-0658552-A1 | Process for the preparation of alpha-tocopherol derivatives | Eisai Co., Ltd. (JP) | 1995-06-21 | — | — | EP | claimed |
| EP-1778661-B1 | PROCESS FOR THE MANUFACTURE OF CHROMAN DERIVATIVES, ESPECIALLY ALPHA-TOCOPHEROL AND ALKANOATES THEREOF | DSM IP ASSETS BV (NL) | 2014-01-22 | — | — | EP | disclosed |
| US-8431727-B2 | Process for the manufacture of chroman derivatives, especially α-tocopherol and alka-noates thereof | DSM ASSETS B.V. (NL) | 2013-04-30 | — | — | US | disclosed |
| CN-1968943-B | Process for producing chroman derivatives, especially alpha-tocopherol and alkanoates thereof | DSM IP ASSETS BV | 2011-08-10 | — | — | CN | disclosed |
| US-20090176998-A1 | Process for the manufacture of chroman derivatives, especially alpha-tocopherol and alka-noates thereof | DSM ASSETS B.V. (NL) | 2009-07-09 | — | — | US | disclosed |
| CN-1968943-A | Process for producing chroman derivatives, especially alpha-tocopherol and alkanoates thereof | DSM IP ASSETS BV (NL) | 2007-05-23 | — | — | CN | disclosed |
| US-20050277777-A1 | Process for the manufacture of chroman derivatives, especially alpha-tocopherol and alkanoates thereof | BONRATH WERNER | 2005-12-15 | — | — | US | disclosed |
| CN-1052978-C | Process for the preparation of alpha-tocopherol derivatives | EISAI CO LTD (JP) | 2000-05-31 | — | — | CN | disclosed |
| EP-0658552-B1 | Process for the preparation of alpha-tocopherol derivatives | EISAI CO LTD (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5532387-A | CYCLIZATION OF TRIMETHYLHYDROQUINONE AND AN ALKENYL ALCOHOL, REUSABLE CATALYST, IIIB FLUOROSULFONATE, NITRATE, SULFATE, OR FLUOROALKYLSULFONATE | EISAI CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| CN-1108254-A | Process for the preparation of alpha-tocopherol derivatives | EISAI CO LTD (JP) | 1995-09-13 | — | — | CN | disclosed |
| EP-0658552-A1 | Process for the preparation of alpha-tocopherol derivatives | Eisai Co., Ltd. (JP) | 1995-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277777-A1 | Process for the manufacture of chroman derivatives, especially alpha-tocopherol and alkanoates thereof | TTPA, TCP1, TST | KAT6A 125/4885MYC 3144/4885TSHR 186/4885 |
| US-20090176998-A1 | Process for the manufacture of chroman derivatives, especially alpha-tocopherol and alka-noates thereof | TTPA, TCP1, TBL2 | KAT6A 128/4885MYC 3041/4885TSHR 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.