Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232628 | 0.85 | LMNA (0.51) | LMNASMN1; SMN2CYP2C19HIF1A | |
| Ioglucomide SCHEMBL668426 | 0.83 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL11523450 | 0.81 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL11524954 | 0.80 | LMNA (0.46) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL11526793 | 0.79 | LMNA (0.45) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL11224662 | 0.79 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL11232347 | 0.78 | LMNA (0.44) | LMNASMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL11217136 | 0.78 | SMN1; SMN2 (0.45) | LMNASMN1; SMN2 | |
| SCHEMBL9239081 | 0.77 | LMNA (0.49) | LMNASMN1; SMN2CYP2C19 | |
| SCHEMBL13220206 | 0.76 | LMNA (0.50) | LMNASMN1; SMN2CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005364-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-01-08 | — | — | WO | claimed |
| WO-2009005364-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-01-08 | — | — | WO | disclosed |