Glycerin

Glycerin

SCHEMBL3920132

C=C(C)C(=O)OC.OCC(O)CO

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.65
TSHR P16473 3/20 0.47
LMNA P02545 2/20 0.39
TGFBR1 P36897 2/20 0.38
THRB P10828 1/20 0.35
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
PLA2G2C Q5R387 1/20 0.30
TET2 Q6N021 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL23495996 0.96 ALDH1A1 (0.60) ALDH1A1TSHRLMNATGFBR1THRB
Methacrylic Acid SCHEMBL29080036 0.94 ALDH1A1 (0.58) ALDH1A1TSHRLMNATGFBR1THRB
Methacrylic Acid SCHEMBL8355193 0.94 ALDH1A1 (0.58) ALDH1A1TSHRLMNATGFBR1THRB
Glycerin SCHEMBL28643209 0.89 ALDH1A1 (0.52) ALDH1A1TSHRLMNATGFBR1THRB
SCHEMBL28207390 0.88 ALDH1A1 (0.56) ALDH1A1TSHRLMNATGFBR1THRB
Propylene Glycol SCHEMBL21836014 0.87 ALDH1A1 (0.65) ALDH1A1TSHRTGFBR1THRBMGAM
SCHEMBL8731726 0.87 TSHR (0.58) ALDH1A1TSHRLMNATGFBR1THRB
SCHEMBL28321822 0.85 ALDH1A1 (0.52) ALDH1A1TSHRTGFBR1THRB
Mannitol SCHEMBL28871183 0.83 ALDH1A1 (0.60) ALDH1A1TSHRLMNATGFBR1THRB
Propylene Glycol SCHEMBL28979820 0.83 ALDH1A1 (0.60) ALDH1A1TSHRTGFBR1THRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160220503-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF ETH ZURICH (CH) 2016-08-04 US claimed
US-20140186445-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF ETH ZURICH (CH) 2014-07-03 US claimed
EP-2709601-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF ETH Zurich (CH) 2014-03-26 EP claimed
CN-103507282-A Method for manufacturing contact lens and contact lens CHIANG KUO-CHING 2014-01-15 CN claimed
WO-2012156065-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF ETH ZURICH (CH) 2012-11-22 WO claimed
EP-2524690-A1 Method for making customised nanoparticles, nanoparticles and use thereof ETH Zurich (CH) 2012-11-21 EP claimed
US-20090200692-A1 Method for manufacturing a silicone contact lens having a hydrophilic surface CHANG JAME 2009-08-13 US claimed
CN-110835486-B Antifouling composition 佐敦有限公司 2022-11-29 CN disclosed
CN-109983083-B Antifouling composition 佐敦有限公司 2021-08-17 CN disclosed
CN-110835486-A Antifouling composition 佐敦有限公司 2020-02-25 CN disclosed
CN-105440226-B Silicon-containing hydrogel contact lens and manufacturing method of silicon-containing hydrogel 望隼科技股份有限公司 2017-10-27 CN disclosed
US-9708450-B2 Silicone hydrogel contact lens and method for manufacturing the same VIZIONFOCUS INC. (TW) 2017-07-18 US disclosed
CN-106244095-A Acrylate base adhesive and preparation method thereof 苏州工业园区莱博特瑞新材料科技有限公司 2016-12-21 CN disclosed
US-20060111535-A1 Processes including initiation of polymerization by hydrogen atom donation GRIDNEV ALEXEI A 2006-05-25 US disclosed
US-7022792-B2 Initiation of polymerization by hydrogen atom donation E. I. DUPONT DE NEMOURS AND COMPANY (US) 2006-04-04 US disclosed
WO-2005090414-A1 INITIATION OF POLYMERIZATION BY HYDROGEN ATOM DONATION E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-09-29 WO disclosed
US-20050209418-A1 Initiation of polymerization by hydrogen atom donation E. I. DU PONT DE NEMOURS AND COMPANY 2005-09-22 US disclosed
EP-0044832-A4 PRODUCTION OF POLY(POLYISOCYANATE SILICATE)SOLID OR CELLULAR SOLID UTILIZING ALKALI METAL SILICATES. BLOUNT DAVID H 1982-07-06 EP disclosed
EP-0044832-A1 PRODUCTION OF POLY(POLYISOCYANATE SILICATE)SOLID OR CELLULAR SOLID UTILIZING ALKALI METAL SILICATES BLOUNT, David H. (US) 1982-02-03 EP disclosed
WO-1981002300-A1 PRODUCTION OF POLY(POLYISOCYANATE SILICATE)SOLID OR CELLULAR SOLID UTILIZING ALKALI METAL SILICATES BLOUNT D 1981-08-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140186445-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF MSN, CD14, SAMM50 ALDH1A1 2301/4885TSHR 3424/4885LMNA 790/4885
US-20160220503-A1 METHOD FOR MAKING CUSTOMISED NANOPARTICLES, NANOPARTICLES AND USES THEREOF MSN, CD14, SAMM50 ALDH1A1 2301/4885TSHR 3424/4885LMNA 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.