Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18937751 | 0.85 | MAPT (0.36) | PKMALDH1A1TDP1MAPTTP53 | |
| SCHEMBL28342145 | 0.85 | ALDH1A1 (0.42) | PKMALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL27961261 | 0.81 | ALDH1A1 (0.38) | PKMALDH1A1TDP1MAPTTP53 | |
| SCHEMBL17364540 | 0.78 | TDP1 (0.42) | PKMALDH1A1TDP1MAPTCYP3A4 | |
| SCHEMBL30600835 | 0.77 | GRIN2D (0.41) | PKMALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL8884170 | 0.77 | GRIN2D (0.41) | PKMALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL31261978 | 0.77 | GRIN2D (0.41) | PKMALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL18322671 | 0.77 | PKM (0.42) | PKMALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL12510901 | 0.77 | GRIN2D (0.41) | PKMALDH1A1TDP1MAPTKDM4E | |
| SCHEMBL31539799 | 0.77 | GRIN2D (0.41) | PKMALDH1A1TDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040703-A2 | DERIVATIVES OF 2-BENZOYL-IMIDAZOPYRIDINES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008003854-A2 | DERIVATIVES OF 2-BENZOYL-IMIDAZOPYRIDINES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2008-01-10 | — | — | WO | disclosed |