Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.61 |
| ▸ | PTGES | O14684 | 3/20 | 0.47 |
| ▸ | MMP13 | P45452 | 9/20 | 0.46 |
| ▸ | MMP9 | P14780 | 8/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP14 | P50281 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 2/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | MMP16 | P51512 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097680 | 0.91 | MMP1 (0.53) | MMP1PTGESMMP13MMP9MMP2 | |
| SCHEMBL7350800 | 0.87 | BMP1 (0.54) | MMP1PTGESMMP13MMP9ADAM17 | |
| SCHEMBL3916840 | 0.86 | MMP1 (0.63) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL7348771 | 0.86 | BMP1 (0.53) | MMP1PTGESMMP13MMP9ADAM17 | |
| SCHEMBL3915124 | 0.84 | MMP1 (0.60) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL3914710 | 0.84 | MMP1 (0.78) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL3914343 | 0.84 | MMP1 (0.60) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL3920825 | 0.83 | MMP1 (0.59) | MMP1MMP13MMP9MMP2MMP3 | |
| SCHEMBL6699509 | 0.81 | MMP1 (0.84) | MMP1PTGESMMP13MMP9MMP2 | |
| SCHEMBL3915716 | 0.81 | MMP1 (0.57) | MMP1MMP13MMP9MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-7504537-B2 | Hydroxamic acid derivative and MMP inhibitor containing the same as active ingredient | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |