Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3925125 | 0.99 | KCNA3 (0.45) | KCNA3HTR2CCA12CA1CA2 | |
| Trifluoroacetic Acid SCHEMBL3913356 | 0.97 | HTR2C (0.45) | KCNA3HTR2CALDH1A1MCL1TTR | |
| Trifluoroacetic Acid SCHEMBL5728404 | 0.93 | HTR2C (0.44) | KCNA3HTR2CALDH1A1MCL1TTR | |
| SCHEMBL3920121 | 0.90 | KCNA3 (0.51) | KCNA3CA12CA1CA9ALDH1A1 | |
| SCHEMBL3914736 | 0.89 | KCNA3 (0.50) | KCNA3CA12CA1CA9ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3910499 | 0.86 | ALDH1A1 (0.51) | KCNA3HTR2CALDH1A1MCL1PPARA | |
| SCHEMBL3911254 | 0.86 | KCNA3 (0.49) | KCNA3CA12CA1CA9ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL3912558 | 0.85 | HTR2C (0.39) | KCNA3HTR2CALDH1A1MCL1MAOB | |
| Trifluoroacetic Acid SCHEMBL3913747 | 0.84 | KCNA3 (0.44) | KCNA3CA12CA1CA2CA9 | |
| Trifluoroacetic Acid SCHEMBL3922171 | 0.83 | PIM1 (0.44) | KCNA3CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667988-B1 | COUMARINS AS INOS INHIBITORS | AVENTIS PHARMA INC (US) | 2013-04-10 | — | — | EP | disclosed |
| US-7538233-B2 | Coumarins as iNOS inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2009-05-26 | — | — | US | disclosed |
| EP-1667988-A1 | COUMARINS AS INOS INHIBITORS | Aventis Pharmaceuticals Inc. (US) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026143-A1 | COUMARINS AS INOS INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2005-03-24 | — | — | WO | disclosed |
| US-20050054681-A1 | Coumarins as iNOS inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2005-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054681-A1 | Coumarins as iNOS inhibitors | NOS2, NOS1, NOS3 | KCNA3 3807/4885HTR2C 2770/4885CA12 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.