SCHEMBL3923623

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3918988	0.91	ATM (0.43)	ATMRIPK1SIGMAR1KDM4EALDH1A1
	SCHEMBL2939186	0.89	ATM (0.43)	ATMRIPK1SIGMAR1KDM4EALDH1A1
	SCHEMBL5151456	0.89	CYP2C9 (0.44)	ATMRIPK1SIGMAR1KDM4EALDH1A1
	SCHEMBL3926088	0.88	CXCR3 (0.41)	RIPK1CXCR3POLBCYP2D6
	SCHEMBL4032393	0.88	SIGMAR1 (0.39)	ATMRIPK1SIGMAR1KDM4EALDH1A1
	SCHEMBL1799713	0.88	RIPK1 (0.46)	ATMRIPK1SIGMAR1KDM4EALDH1A1
	SCHEMBL4032741	0.87	ATM (0.44)	ATMRIPK1SIGMAR1KDM4EALDH1A1
	SCHEMBL4038603	0.87	ATM (0.42)	ATMRIPK1SIGMAR1KDM4EALDH1A1
	SCHEMBL1803348	0.87	GRM5 (0.43)	ATMRIPK1SIGMAR1ALDH1A1KMT2A
	SCHEMBL1800386	0.86	NPC1 (0.41)	ATMRIPK1SIGMAR1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.