Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 3/20 | 0.33 |
| ▸ | F3 | P13726 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924242 | 1.00 | ALDH1A1 (0.35) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL16415992 | 0.90 | ALDH1A1 (0.38) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL16415993 | 0.90 | ALDH1A1 (0.38) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL16418357 | 0.90 | ALDH1A1 (0.38) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL5081580 | 0.86 | ALDH1A1 (0.39) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL15237148 | 0.86 | ALDH1A1 (0.39) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL5081582 | 0.86 | ALDH1A1 (0.39) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL4492259 | 0.83 | THRB (0.42) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL7122442 | 0.83 | THRB (0.42) | ALDH1A1CYP19A1MAPTPPARGOXER1 | |
| SCHEMBL30629416 | 0.83 | NFKB1 (0.37) | ALDH1A1CYP19A1MAPTPPARGOXER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1837326-B1 | Organoleptic compounds and their use in perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2013-04-10 | — | — | EP | disclosed |
| US-7531489-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-05-12 | — | — | US | disclosed |
| US-20080242586-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-10-02 | — | — | US | disclosed |
| US-7402551-B2 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2008-07-22 | — | — | US | disclosed |
| EP-1837326-A1 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-09-26 | — | — | EP | disclosed |
| US-20070219102-A1 | Organoleptic compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242586-A1 | ORGANOLEPTIC COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | TRPA1, CYP2E1, CPT1A | ALDH1A1 427/4885CYP19A1 460/4885MAPT 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.