Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 8/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30462849 | 1.00 | FDPS (0.71) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL458083 | 0.94 | FDPS (0.81) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL30462864 | 0.94 | FDPS (0.71) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL4409432 | 0.94 | FDPS (0.71) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL30462879 | 0.94 | FDPS (0.81) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL5974454 | 0.92 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL5974612 | 0.90 | FDPS (0.75) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL13590011 | 0.90 | FDPS (0.75) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL7661907 | 0.90 | FDPS (0.86) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL28335185 | 0.88 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283936-A | Substituted amino ether-containing 2, 2-dimethyl benzopyran derivative and salt or solvate thereof, preparation and application thereof, and composition | 沈阳药科大学 | 2023-06-23 | — | — | CN | disclosed |
| US-20230115176-A1 | Complement Modulators and Related Methods | RA PHARMACEUTICALS, INC. | 2023-04-13 | — | — | US | disclosed |
| EP-3947352-A1 | COMPLEMENT MODULATORS AND RELATED METHODS | RA Pharmaceuticals, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020205501-A1 | COMPLEMENT MODULATORS AND RELATED METHODS | RA PHARMACEUTICALS, INC. (US) | 2020-10-08 | — | — | WO | disclosed |
| US-8361996-B2 | Imidazolyl substituted steroidal and indan-1-one derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2013-01-29 | — | — | US | disclosed |
| CN-101291950-B | Novel series of imidazolyl substituted steroidal and indan-1-one derivatives | COUNCIL SCIENT IND RES | 2013-01-02 | — | — | CN | disclosed |
| EP-1934241-B1 | NOVEL SERIES OF IMIDAZOLYL SUBSTITUTED STEROIDAL AND INDAN-1-ONE DERIVATIVES | COUNCIL SCIENT IND RES (IN) | 2012-11-14 | — | — | EP | disclosed |
| EP-1698635-B1 | BENZIMIDAZOLE DERIVATIVES AND MEDICAL USES THEREOF | KISSEI PHARMACEUTICAL (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-7547680-B2 | Benzimidazole derivatives and medical uses thereof | KISSEI PHARMACEUTICALS, CO., LTD. (JP) | 2009-06-16 | — | — | US | disclosed |
| US-20090137541-A1 | Novel Series of Imidazolyl Substituted Steroidal and Indan-1-One Derivatives | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2009-05-28 | — | — | US | disclosed |
| CN-101291950-A | Novel series of imidazolyl substituted steroidal and indan-1-one derivatives | COUNCIL SCIENT IND RES (IN) | 2008-10-22 | — | — | CN | disclosed |
| EP-1934241-A2 | NOVEL SERIES OF IMIDAZOLYL SUBSTITUTED STEROIDAL AND INDAN-1-ONE DERIVATIVES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2008-06-25 | — | — | EP | disclosed |
| US-20080038242-A1 | Benzimidazole derivatives and medical uses thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | US | disclosed |
| WO-2007031833-A2 | NOVEL SERIES OF IMIDAZOLYL SUBSTITUTED STEROIDAL AND INDAN-1-ONE DERIVATIVES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2007-03-22 | — | — | WO | disclosed |
| EP-1698635-A1 | BENZIMIDAZOLE DERIVATIVES AND MEDICAL USES THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230115176-A1 | Complement Modulators and Related Methods | C5, C9, C1QBP | FDPS 646/4885ALDH1A1 4659/4885TSHR 3798/4885 |
| US-20080038242-A1 | Benzimidazole derivatives and medical uses thereof | SLCO1B3, SLCO2A1, SLCO2B1 | FDPS 1459/4885ALDH1A1 1096/4885TSHR 1254/4885 |
| US-20090137541-A1 | Novel Series of Imidazolyl Substituted Steroidal and Indan-1-One Derivatives | NR5A1, NR3C2, CYP17A1 | FDPS 715/4885ALDH1A1 1121/4885TSHR 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.