Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 10/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 7/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30462879 | 1.00 | FDPS (0.81) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL28335185 | 0.94 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL3924488 | 0.94 | FDPS (0.71) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL30462849 | 0.94 | FDPS (0.71) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL5254439 | 0.94 | FDPS (0.81) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL9442186 | 0.92 | FDPS (0.90) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL8719147 | 0.90 | FDPS (0.87) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL9442183 | 0.90 | FDPS (0.87) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL5973815 | 0.90 | FDPS (1.00) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL686103 | 0.87 | FDPS (0.81) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190501-A1 | PROCESSES FOR THE PREPARATION OF 4'-[3-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINO]PROPOXY]-3'-METHOXYACETOPHENONE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-07-25 | — | — | US | claimed |
| WO-2012032532-A1 | \"PROCESSES FOR THE PREPARATION OF 4'-[3-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINO]PROPOXY]-3'-METHOXYACETOPHENONE AND INTERMEDIATES THEREOF\ | SYMED LABS LIMITED (IN) | 2012-03-15 | — | — | WO | claimed |
| CN-116283936-A | Substituted amino ether-containing 2, 2-dimethyl benzopyran derivative and salt or solvate thereof, preparation and application thereof, and composition | 沈阳药科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-110283155-B | Halogenated alkoxy coumarin flame-retardant ultraviolet-blue light absorber and preparation method thereof | 广东省测试分析研究所（中国广州分析测试中心） | 2021-03-26 | — | — | CN | disclosed |
| US-20160113900-A1 | INHIBITORS OF MITOCHONDRIAL STAT3 AND USES THEREOF IN MODULATION OF MAST CELL EXOCYTOSIS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2016-04-28 | — | — | US | disclosed |
| US-9000221-B2 | Processes for the preparation of 4′-[3-[4-(6-Fluoro-1 ,2-benzisoxazol-3-yl)piperidino]propoxy]-3′-methoxyacetophenone and intermediates thereof | SYMED LABS LIMITED (IN) | 2015-04-07 | — | — | US | disclosed |
| US-9000221-B2 | Processes for the preparation of 4′-[3-[4-(6-Fluoro-1 ,2-benzisoxazol-3-yl)piperidino]propoxy]-3′-methoxyacetophenone and intermediates thereof | SYMED LABS LIMITED (IN) | 2015-04-07 | — | — | US | disclosed |
| US-9000221-B2 | Processes for the preparation of 4′-[3-[4-(6-Fluoro-1 ,2-benzisoxazol-3-yl)piperidino]propoxy]-3′-methoxyacetophenone and intermediates thereof | SYMED LABS LIMITED (IN) | 2015-04-07 | — | — | US | disclosed |
| US-20130190501-A1 | PROCESSES FOR THE PREPARATION OF 4'-[3-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINO]PROPOXY]-3'-METHOXYACETOPHENONE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-07-25 | — | — | US | disclosed |
| US-20130190501-A1 | PROCESSES FOR THE PREPARATION OF 4'-[3-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINO]PROPOXY]-3'-METHOXYACETOPHENONE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-07-25 | — | — | US | disclosed |
| US-20130190501-A1 | PROCESSES FOR THE PREPARATION OF 4'-[3-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINO]PROPOXY]-3'-METHOXYACETOPHENONE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-07-25 | — | — | US | disclosed |
| US-5552414-A | 1-(1H-indolyloxyalkyl)-4-(heteroaryl) piperidines and related compounds useful as antipsychotics and analgesics | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-09-03 | — | — | US | disclosed |
| US-5550130-A | ANTIPSYCHOTIC AGENTS, ANALGESICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1996-08-27 | — | — | US | disclosed |
| WO-1995011680-A1 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-05-04 | — | — | WO | disclosed |
| US-5364866-A | Side effect reduction | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5358999-A | Polyvinyl acetals | ULANO CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| EP-0612318-A1 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5330877-A | Photoresists based on quaternary ammonium derivatives of an acetal resin | ULANO CORPORATION (US) | 1994-07-19 | — | — | US | disclosed |
| EP-0542136-A1 | Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgetics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-05-19 | — | — | EP | disclosed |
| WO-1993009102-A1 | HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1993-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190501-A1 | PROCESSES FOR THE PREPARATION OF 4'-[3-[4-(6-FLUORO-1,2-BENZISOXAZOL-3-YL)PIPERIDINO]PROPOXY]-3'-METHOXYACETOPHENONE AND INTERMEDIATES THEREOF | CYP4B1, CYP4X1, CYP3A4 | FDPS 168/4885ALDH1A1 33/4885TSHR 4628/4885 |
| US-20160113900-A1 | INHIBITORS OF MITOCHONDRIAL STAT3 AND USES THEREOF IN MODULATION OF MAST CELL EXOCYTOSIS | STAT3, JAK2, MAVS | FDPS 3664/4885ALDH1A1 3264/4885TSHR 3109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.