Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 8/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30462864 | 1.00 | FDPS (0.71) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL3924488 | 0.94 | FDPS (0.71) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL30462849 | 0.94 | FDPS (0.71) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL5254439 | 0.94 | FDPS (0.81) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL7661907 | 0.90 | FDPS (0.86) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL5974454 | 0.88 | FDPS (0.77) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL30462879 | 0.87 | FDPS (0.81) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL458083 | 0.87 | FDPS (0.81) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL5974612 | 0.87 | FDPS (0.75) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL13590011 | 0.87 | FDPS (0.75) | FDPSALDH1A1TSHRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283936-A | Substituted amino ether-containing 2, 2-dimethyl benzopyran derivative and salt or solvate thereof, preparation and application thereof, and composition | 沈阳药科大学 | 2023-06-23 | — | — | CN | disclosed |
| EP-1994000-B1 | WATER-SOLUBLE CC-1065 ANALOGS AND THEIR CONJUGATES | SYNTARGA BV (NL) | 2017-08-23 | — | — | EP | disclosed |
| WO-2015038426-A1 | SELF-IMMOLATIVE LINKERS CONTAINING MANDELIC ACID DERIVATIVES, DRUG-LIGAND CONJUGATES FOR TARGETED THERAPIES AND USES THEREOF | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | disclosed |
| US-8940784-B2 | Water-soluble CC-1065 analogs and their conjugates | SYNTARGA B.V. (NL) | 2015-01-27 | — | — | US | disclosed |
| US-20090318668-A1 | Water-Soluble CC-1065 Analogs and Their Conjugates | Georg-August-Universität Göttingen Stiftung öffentlichen Rechts (ohne Bereich Humanmedizin) (DE) | 2009-12-24 | — | — | US | disclosed |
| CN-101415679-A | Water-soluble CC-1065 analogs and conjugates thereof | SINTAGAR B V (NL) | 2009-04-22 | — | — | CN | disclosed |
| EP-1994000-A2 | WATER-SOLUBLE CC-1065 ANALOGS AND THEIR CONJUGATES | Syntarga B.V. (NL) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007089149-A2 | WATER-SOLUBLE CC-1065 ANALOGS AND THEIR CONJUGATES | SYNTARGA B.V. (NL) | 2007-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318668-A1 | Water-Soluble CC-1065 Analogs and Their Conjugates | PCNA, DCK, BAD | FDPS 4530/4885ALDH1A1 2365/4885TSHR 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.