SCHEMBL3926243

SCHEMBL3926243

CCCCCCCCCCCCCCCC(O)N1CCCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.41
SPHK1 Q9NYA1 2/20 0.41
FFAR1 O14842 1/20 0.41
LMNA P02545 2/20 0.40
L3MBTL1 Q9Y468 3/20 0.38
CYP2D6 P10635 2/20 0.38
MAPT P10636 2/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CETP P11597 1/20 0.38
HTT P42858 1/20 0.38
UBE2N P61088 1/20 0.38
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3924873 0.98 L3MBTL1 (0.40) GPR84SPHK1FFAR1LMNAL3MBTL1
SCHEMBL28284934 0.98 L3MBTL1 (0.40) GPR84SPHK1FFAR1LMNAL3MBTL1
SCHEMBL3928047 0.98 L3MBTL1 (0.39) GPR84SPHK1FFAR1LMNAL3MBTL1
SCHEMBL3932212 0.96 L3MBTL1 (0.41) GPR84SPHK1FFAR1LMNAL3MBTL1
SCHEMBL8972636 0.91 GPR84 (0.43) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL3921352 0.91 GPR84 (0.43) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL10440046 0.89 HRH3 (0.42) L3MBTL1MAPTMAPK1NPSR1MEN1
SCHEMBL3932573 0.89 GPR84 (0.40) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL11117641 0.82 GNAI3 (0.43) GPR84SPHK1FFAR1LMNA
SCHEMBL8972603 0.82 KCNA5 (0.44) GPR84SPHK1FFAR1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572837-B2 Process for the production of flexible polyurethane foams TOSOH CORPORATION (JP) 2009-08-11 US disclosed
US-20030144371-A1 Catalyzing the copolymerization in presence of imidazole compounds, free of tin comound, forming polyetherurethane copolymers TOSOH CORPORATION (JP) 2003-07-31 US disclosed
EP-1312630-A1 Process for the production of flexible polyurethane foams Tosoh Corporation (JP) 2003-05-21 EP disclosed