Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.67 |
| ▸ | RELA | Q04206 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37686 | 0.84 | NPC1 (0.63) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL14814817 | 0.77 | PKM (0.61) | MAPTSMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL1916174 | 0.77 | PKM (0.65) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL37919 | 0.73 | MAPT (0.56) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL1915688 | 0.73 | PKM (0.56) | NPC1RAB9APKMRORCHPGD | |
| SCHEMBL3598222 | 0.72 | PKM (0.65) | MAPTCYP1A2PKMRORCHPGD | |
| SCHEMBL1916623 | 0.72 | RORC (0.58) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL38629 | 0.72 | MAPT (0.74) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL38117 | 0.71 | GSTO1 (0.58) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL1800878 | 0.70 | ALDH1A1 (0.65) | PKMRORCALDH1A1KDM4EAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |