Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 5/20 | 0.31 |
| ▸ | MAOA | P21397 | 4/20 | 0.31 |
| ▸ | MAOB | P27338 | 4/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.31 |
| ▸ | CCNC | P24863 | 2/20 | 0.31 |
| ▸ | CDK8 | P49336 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30669251 | 0.75 | FADS1 (0.50) | KDM1AMAOAMAOBRCOR1KDM1B | |
| SCHEMBL6099462 | 0.74 | TNKS (0.45) | TNKSELOVL6KDM1AMAOAMAOB | |
| SCHEMBL4885970 | 0.73 | EGLN2 (0.35) | EGLN2TNKSELOVL6PIK3CAMTOR | |
| SCHEMBL3926368 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL3602045 | 0.72 | TNKS (0.39) | EGLN2TNKSPIK3CAMTORKDM1A | |
| SCHEMBL3587464 | 0.72 | PSEN1 (0.38) | EGLN2ELOVL6MTORCMA1 | |
| SCHEMBL30980973 | 0.71 | PIK3CD (0.39) | EGLN2TNKSPER2CRY2KDM1A | |
| SCHEMBL1031728 | 0.70 | TNKS (0.42) | EGLN2TNKSPIK3CAMTORKDM1A | |
| SCHEMBL8349969 | 0.70 | BPTF (0.43) | EGLN2TNKSPIK3CAMTORCCNC | |
| SCHEMBL26298453 | 0.70 | EGLN2 (0.40) | EGLN2TNKSPIK3CAMTORIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007747-A2 | HYDANTOIN DERIVATIVES USED AS MMP12 INHIBITORS | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | WO | disclosed |