Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931641 | 0.79 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTTDP1MEN1 | |
| SCHEMBL10068461 | 0.76 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4ETDP1NPC1 | |
| SCHEMBL12869799 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTTDP1MEN1 | |
| SCHEMBL3931636 | 0.74 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTKDM4ETDP1 | |
| SCHEMBL9613341 | 0.74 | ALDH1A1 (0.69) | ALDH1A1KDM4ENPC1RAB9AADRB2 | |
| SCHEMBL4710134 | 0.73 | TDP1 (0.54) | ALDH1A1SMN1; SMN2MAPTKDM4ETDP1 | |
| SCHEMBL2025129 | 0.73 | ALDH1A1 (0.57) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL10037333 | 0.73 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4ETDP1NPC1 | |
| SCHEMBL14301138 | 0.72 | ALDH1A1 (0.71) | ALDH1A1KDM4ENPC1RAB9APTPN1 | |
| SCHEMBL28747178 | 0.72 | ALDH1A1 (0.67) | ALDH1A1KDM4ETDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044083-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008008907-A2 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008008912-A1 | ANTIVIRAL AGENTS | GENELABS TECHNOLOGIES, INC. (US) | 2008-01-17 | — | — | WO | disclosed |