Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MPO | P05164 | 8/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21556903 | 0.83 | IAPP (0.45) | MTNR1AMPOMTNR1BNQO2 | |
| SCHEMBL3926227 | 0.83 | MPO (0.55) | MTNR1AMPOSLC6A4 | |
| Hydrochloric Acid SCHEMBL6997774 | 0.81 | MPO (0.53) | MTNR1AMPOSLC6A4 | |
| SCHEMBL3916714 | 0.78 | TAAR1 (0.55) | MTNR1AMPO | |
| SCHEMBL30496749 | 0.78 | TAAR1 (0.55) | MTNR1AMPO | |
| Hydrochloric Acid SCHEMBL28482472 | 0.77 | TAAR1 (0.53) | MTNR1AMPO | |
| SCHEMBL14868503 | 0.72 | IAPP (0.41) | MTNR1AMPOMTNR1BNQO2 | |
| SCHEMBL10310457 | 0.71 | TAAR1 (0.50) | MTNR1AMTNR1B | |
| SCHEMBL30496716 | 0.71 | TAAR1 (0.50) | MTNR1AMTNR1B | |
| SCHEMBL10310269 | 0.71 | TAAR1 (0.55) | MTNR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060127309-A1 | Imaging agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2006-06-15 | — | — | US | claimed |
| US-10259781-B2 | Imaging agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-04-16 | — | — | US | disclosed |
| US-20170190658-A1 | IMAGING AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-07-06 | — | — | US | disclosed |
| US-20150246142-A1 | IMAGING AGENTS | UNIV MICHIGAN (US) | 2015-09-03 | — | — | US | disclosed |
| US-7534418-B2 | Imaging agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-05-19 | — | — | US | disclosed |
| US-20060127309-A1 | Imaging agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246142-A1 | IMAGING AGENTS | SLC18A1, VHL, GDI1 | MTNR1A 401/4885MPO 2156/4885MEP1B 324/4885 |
| US-20060127309-A1 | Imaging agents | MPI, NPC1, NPC1L1 | MTNR1A 689/4885MPO 1947/4885MEP1B 1511/4885 |
| US-10259781-B2 | Imaging agents | SLC18A1, VHL, GDI1 | MTNR1A 401/4885MPO 2156/4885MEP1B 324/4885 |
| US-20170190658-A1 | IMAGING AGENTS | SLC18A1, VHL, GDI1 | MTNR1A 401/4885MPO 2156/4885MEP1B 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.