Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MPO | P05164 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14868503 | 0.87 | IAPP (0.41) | IAPPMTNR1AMPOCA2ADAMTS4 | |
| SCHEMBL3926227 | 0.86 | MPO (0.55) | MTNR1AMPOCA2HSD17B10TAAR1 | |
| Hydrochloric Acid SCHEMBL6997774 | 0.84 | MPO (0.53) | MTNR1AMPOCA2HSD17B10TAAR1 | |
| SCHEMBL3928151 | 0.83 | MTNR1A (0.42) | MTNR1AMPOMTNR1BNQO2 | |
| SCHEMBL4827827 | 0.82 | PIM1 (0.41) | IAPPMTNR1ACA2ADAMTS4ALDH1A1 | |
| SCHEMBL14868471 | 0.81 | IAPP (0.39) | IAPPMTNR1AMPOMTNR1BNQO2 | |
| SCHEMBL14868428 | 0.81 | IAPP (0.41) | IAPPMTNR1AMPOCA2CA1 | |
| SCHEMBL22353000 | 0.79 | IAPP (0.39) | IAPPMTNR1AMPOCA2ADAMTS4 | |
| SCHEMBL11576902 | 0.77 | IAPP (0.54) | IAPPMTNR1AMPOALOX5MTNR1B | |
| SCHEMBL14868439 | 0.76 | IAPP (0.43) | IAPPMTNR1AMPOMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |