Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929580 | 0.85 | L3MBTL1 (0.46) | AGBL2GAAALDH1A1PPARGPPARA | |
| SCHEMBL3928210 | 0.83 | AGBL2 (0.68) | AGBL2FFAR1GAAALDH1A1MAPT | |
| SCHEMBL3936887 | 0.81 | AGBL2 (0.52) | AGBL2FFAR1GAAALDH1A1MAPT | |
| SCHEMBL3932258 | 0.80 | MAPT (0.56) | AGBL2GAAALDH1A1MAPTKDM4E | |
| SCHEMBL3928786 | 0.78 | PTGDR2 (0.48) | AGBL2FFAR1POLQRXRAFFAR4 | |
| SCHEMBL4011125 | 0.73 | ALDH1A1 (0.37) | GAAALDH1A1MAPTKDM4EPTGDR2 | |
| SCHEMBL3930078 | 0.73 | PTGDR2 (0.50) | AGBL2FFAR1GAAALDH1A1MAPT | |
| SCHEMBL3924887 | 0.71 | AGBL2 (0.55) | AGBL2GAAALDH1A1MAPTKDM4E | |
| SCHEMBL5717719 | 0.71 | MAPT (0.58) | AGBL2FFAR1GAAALDH1A1MAPT | |
| SCHEMBL29010077 | 0.71 | FFAR1 (0.66) | AGBL2FFAR1GAAALDH1A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |