Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | POLQ | O75417 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRG | P48443 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926909 | 0.85 | MAPK1 (0.44) | PTGDR2AGBL2S1PR1PTGS1PTGS2 | |
| SCHEMBL3936887 | 0.80 | AGBL2 (0.52) | AGBL2GLAPOLQRXRAKMT2A | |
| SCHEMBL3928210 | 0.80 | AGBL2 (0.68) | PTGDR2AGBL2FFAR4GLAPOLQ | |
| SCHEMBL3927004 | 0.80 | RXRA (0.47) | AGBL2S1PR1LTB4RGLARXRA | |
| SCHEMBL3932258 | 0.79 | MAPT (0.56) | AGBL2GLACYP2C19KMT2A | |
| SCHEMBL3935935 | 0.78 | AGBL2 (0.51) | PTGDR2AGBL2FFAR4GLAPOLQ | |
| SCHEMBL4006240 | 0.75 | KDM4E (0.39) | PTGDR2FFAR4GLACYP2C9CYP2C19 | |
| SCHEMBL10507885 | 0.73 | LTB4R (0.48) | LTB4RRXRARXRBRXRGCYP2C19 | |
| SCHEMBL3930078 | 0.72 | PTGDR2 (0.50) | PTGDR2AGBL2S1PR1PTGS2FFAR1 | |
| Azelaic Acid SCHEMBL27562613 | 0.71 | MAPT (0.57) | AGBL2GLACYP2C19KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |