Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929382 | 0.88 | GPR119 (0.56) | SMN1; SMN2LMNAKMT2AMEN1CYP2C19 | |
| SCHEMBL7983921 | 0.81 | EPHX2 (0.62) | HDAC1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL7984857 | 0.79 | EPHX2 (0.65) | HDAC1SMN1; SMN2LMNAMAPTEPHX2 | |
| SCHEMBL27022355 | 0.78 | ALDH1A1 (0.71) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL2340177 | 0.77 | GPR119 (0.71) | GPR119 | |
| SCHEMBL7982523 | 0.77 | EPHX2 (0.65) | HDAC1SMN1; SMN2LMNAMAPTEPHX2 | |
| SCHEMBL5098897 | 0.76 | GPR119 (0.53) | HDAC1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL1714269 | 0.76 | GPR119 (0.64) | GPR119 | |
| SCHEMBL3974111 | 0.76 | EPHX2 (0.49) | SMN1; SMN2GPR119EPHX2ALDH1A1PKM | |
| SCHEMBL7989749 | 0.76 | EPHX2 (0.64) | HDAC1SMN1; SMN2LMNAMAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |