SCHEMBL392991

SCHEMBL392991

Cc1cccc([O])c1C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
CYP2A6 P11509 2/20 0.36
CYP1A2 P05177 1/20 0.36
TRPA1 O75762 2/20 0.36
ATM Q13315 1/20 0.36
TSHR P16473 3/20 0.35
ACHE P22303 1/20 0.35
ALDH1A1 P00352 5/20 0.35
CA2 P00918 2/20 0.35
CA1 P00915 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
ELANE P08246 1/20 0.33
CD44 P16070 1/20 0.31
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8387574 0.82 GABRA1 (0.48) GABRA1GABRB2CYP2A6CYP1A2TRPA1
SCHEMBL2687017 0.82 GABRA1 (0.48) GABRA1GABRB2CYP2A6CYP1A2TRPA1
SCHEMBL1535127 0.78 CA2 (0.48) GABRA1GABRB2ATMTSHRALDH1A1
SCHEMBL7066555 0.78
SCHEMBL3105850 0.74 MEN1 (0.37) CYP2A6CYP1A2ATMTSHRALDH1A1
SCHEMBL3106196 0.74 CES2 (0.34) ACHECA2
SCHEMBL1927917 0.73 GABRA1 (0.58) GABRA1GABRB2CYP2A6CYP1A2TRPA1
SCHEMBL22663374 0.73 GABRA1 (0.48) GABRA1GABRB2CYP2A6CYP1A2ALDH1A1
SCHEMBL16355401 0.73 GABRA1 (0.47) GABRA1GABRB2CYP2A6CYP1A2TRPA1
SCHEMBL18242325 0.72 CYP2A6 (0.41) GABRA1GABRB2CYP2A6CYP1A2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2473484-B1 ORGANOPHOSPHORUS COMPOUNDS BASED ON TETRAPHENOL (TP)-SUBSTITUTED STRUCTURES EVONIK DEGUSSA GMBH (DE) 2015-08-19 EP claimed
EP-2886533-A1 Use of Organophosphorus compounds based on tetraphenol (TP)-substituted structures Evonik Degussa GmbH (DE) 2015-06-24 EP claimed
US-9000220-B2 Organophosphorus compounds based on tetraphenol (TP)-substituted structures EVONIK DEGUSSA GMBH (DE) 2015-04-07 US claimed
US-20120197025-A1 ORGANOPHOSPHORUS COMPOUNDS BASED ON TETRAPHENOL (TP)-SUBSTITUTED STRUCTURES EVONIK OXENO GMBH (DE) 2012-08-02 US claimed
EP-2473484-A2 ORGANOPHOSPHORUS COMPOUNDS BASED ON TETRAPHENOL (TP)-SUBSTITUTED STRUCTURES Evonik Oxeno GmbH (DE) 2012-07-11 EP claimed
WO-2011023756-A2 ORGANOPHOSPHORUS COMPOUNDS BASED ON TETRAPHENOL (TP)-SUBSTITUTED STRUCTURES EVONIK OXENO GMBH (DE) 2011-03-03 WO claimed
CN-113387055-B Film, method for producing film, and bag 住友化学株式会社 2024-06-07 CN disclosed
CN-112724302-B Ethylene-alpha-olefin copolymer, process for producing the same, ethylene resin composition, and film 住友化学株式会社 2023-10-31 CN disclosed
US-11643533-B2 Film, method of producing film, and bag SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-09 US disclosed
CN-112638997-B Film and packaging container 住友化学株式会社 2023-04-28 CN disclosed
CN-110352213-B Film 住友化学株式会社 2022-09-09 CN disclosed
US-11149102-B2 Film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-10-19 US disclosed
US-20210284829-A1 FILM, METHOD OF PRODUCING FILM, AND BAG SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-09-16 US disclosed
US-20010053832-A1 Olefin polymerization catalyst and process for producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-20 US disclosed
EP-1153938-A1 CATALYST FOR STEREOREGULAR POLYMERIZATION OF ALPHA-OLEFIN AND PROCESS FOR PRODUCING STEREOREGULAR ALPHA-OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-14 EP disclosed
CN-1314420-A Olefine polymerization catalyst and method for preparing olefine polymer SUMITOMO CHEMICAL CO (JP) 2001-09-26 CN disclosed
EP-1134234-A1 Olefin polymerization catalyst and process for producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-19 EP disclosed
EP-1081167-A1 Olefin polymerization catalyst and process for producing olefin polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-07 EP disclosed
EP-0731805-A1 AMIDES OF ACIDS OF PHOSPHORUS FOR THE EXTRACTION OF METALS ZENECA LIMITED (GB) 1996-09-18 EP disclosed
WO-1995015329-A1 AMIDES OF ACIDS OF PHOSPHORUS FOR THE EXTRACTION OF METALS ZENECA LIMITED (GB) 1995-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120197025-A1 ORGANOPHOSPHORUS COMPOUNDS BASED ON TETRAPHENOL (TP)-SUBSTITUTED STRUCTURES PTMS, HPD, INPPL1 GABRA1 4534/4885GABRB2 4583/4885CYP2A6 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.