SCHEMBL3929965

SCHEMBL3929965

CC(C)(C)c1cccc(-c2nnc(-c3ccc(-c4ccccc4)cc3)o2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 14/20 0.58
RAB9A P51151 14/20 0.58
SMN1; SMN2 Q16637 9/20 0.58
HPGD P15428 5/20 0.58
TSHR P16473 3/20 0.58
NFKB1 P19838 2/20 0.54
NFKB2 Q00653 2/20 0.54
RELA Q04206 2/20 0.54
POLB P06746 2/20 0.54
TP53 P04637 3/20 0.54
MECP2 P51608 1/20 0.54
KDM4E B2RXH2 4/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 2/20 0.53
HSD17B10 Q99714 2/20 0.53
GLA P06280 1/20 0.53
ALOX15 P16050 1/20 0.53
S1PR1 P21453 1/20 0.52
KIF11 P52732 1/20 0.51
MEN1 O00255 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28508820 0.90 KIF11 (0.53) NPC1RAB9ASMN1; SMN2HPGDTSHR
SCHEMBL1421139 0.89 S1PR1 (0.58) NPC1RAB9ASMN1; SMN2HPGDTSHR
SCHEMBL12354585 0.89 S1PR1 (0.61) NPC1RAB9ASMN1; SMN2HPGDTSHR
SCHEMBL8385439 0.86 S1PR1 (0.67) NPC1RAB9ASMN1; SMN2HPGDTSHR
SCHEMBL28982567 0.86 S1PR1 (0.67) NPC1RAB9ASMN1; SMN2HPGDTSHR
SCHEMBL36912 0.86 S1PR1 (0.67) NPC1RAB9ASMN1; SMN2HPGDTSHR
Biphenyl SCHEMBL28899764 0.86 S1PR1 (0.67) NPC1RAB9ASMN1; SMN2HPGDTSHR
SCHEMBL74782 0.86 S1PR1 (0.67) NPC1RAB9ASMN1; SMN2HPGDTSHR
SCHEMBL2623779 0.86 S1PR1 (0.67) NPC1RAB9ASMN1; SMN2HPGDTSHR
SCHEMBL30083 0.85 NPC1 (0.62) NPC1RAB9ASMN1; SMN2HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150028311-A1 DOPED ORGANIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PREPARING SAME OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LT (CN) 2015-01-29 US claimed
US-20140332788-A1 POLYMERIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PREPARING SAME OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD (CN) 2014-11-13 US claimed
US-20140326986-A1 POLYMERIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PREPARING SAME OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2014-11-06 US claimed
EP-2787553-A1 DOPED ORGANIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PREPARING SAME Ocean's King Lighting Science & Technology Co., Ltd. (CN) 2014-10-08 EP claimed
EP-2787552-A1 POLYMERIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PREPARING SAME Ocean's King Lighting Science & Technology Co., Ltd. (CN) 2014-10-08 EP claimed
WO-2024124868-A1 DISPLAY PANEL AND MOBILE TERMINAL 武汉华星光电半导体显示技术有限公司 2024-06-20 WO disclosed
US-11018314-B2 Organic electroluminescent diode and manufacturing method thereof, display panel and display device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2021-05-25 US disclosed
US-20200168831-A1 ORGANIC ELECTROLUMINESCENT DIODE AND MANUFACTURING METHOD THEREOF, DISPLAY PANEL AND DISPLAY DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2020-05-28 US disclosed
US-9123906-B2 Organic electroluminescence device and manufacturing method thereof OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2015-09-01 US disclosed
US-20150028311-A1 DOPED ORGANIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PREPARING SAME OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LT (CN) 2015-01-29 US disclosed
US-20140332788-A1 POLYMERIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PREPARING SAME OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD (CN) 2014-11-13 US disclosed
US-20140326986-A1 POLYMERIC ELECTROLUMINESCENT DEVICE AND METHOD FOR PREPARING SAME OCEAN'S KING LIGHTING SCIENCE & TECHNOLOGY CO., LTD. (CN) 2014-11-06 US disclosed
US-20040215000-A1 Organometallic complexes ISIS INNOVATION LIMITED (GB) 2004-10-28 US disclosed
EP-1115808-B1 DIVALENT LANTHANIDE METAL COMPLEXES ISIS INNOVATION (GB) 2003-11-19 EP disclosed
US-6492526-B1 ORGANOMETALLIC COMPLEXES COMPRISING A DIVALENT LANTHANIDE METAL CATION COMPLEXED WITH FROM ONE TO THREE POLYDENTATE LIGANDS WHICH PREFERABLY CONTAIN ONE OR MORE PYRAZOLYL GROUPS, SUCH AS TRISPYRAZOLYLBORATE ANIONS, ARE USEFUL IN ISIS INNOVATION LIMITED (GB) 2002-12-10 US disclosed
EP-0988353-B1 ORGANOMETALLIC COMPLEXES ISIS INNOVATION (GB) 2002-11-27 EP disclosed
EP-1115808-A1 DIVALENT LANTHANIDE METAL COMPLEXES ISIS INNOVATION LIMITED (GB) 2001-07-18 EP disclosed
WO-2000018851-A1 DIVALENT LANTHANIDE METAL COMPLEXES ISIS INNOVATION LIMITED (GB) 2000-04-06 WO disclosed
EP-0988353-A1 ORGANOMETALLIC COMPLEXES ISIS INNOVATION LIMITED (GB) 2000-03-29 EP disclosed
WO-1998055561-A1 ORGANOMETALLIC COMPLEXES ISIS INNOVATION LIMITED (GB) 1998-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040215000-A1 Organometallic complexes NCLN, NBAS, TLK1 NPC1 4457/4885RAB9A 978/4885SMN1; SMN2 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.