Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11097531 | 1.00 | TSHR (0.57) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL2026119 | 0.98 | LMNA (0.55) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL393044 | 0.90 | LMNA (0.50) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| Succinic Acid SCHEMBL29243141 | 0.83 | GPR84 (0.56) | TSHRLMNAALDH1A1MEN1ALOX15 | |
| Succinic Acid SCHEMBL29243143 | 0.83 | GPR84 (0.56) | TSHRLMNAALDH1A1MEN1ALOX15 | |
| SCHEMBL18695003 | 0.80 | TSHR (0.63) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL23837443 | 0.80 | KMT2A (0.35) | LMNAPMP22ALDH1A1MEN1ALOX15 | |
| SCHEMBL1463490 | 0.79 | — | — | |
| SCHEMBL8069056 | 0.79 | CA2 (0.48) | — | |
| SCHEMBL30041571 | 0.79 | CA2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026611-B1 | ANTIBACTERIAL SULPHONAMIDES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1984-02-01 | — | — | EP | claimed |
| US-4312867-A | USED FOR HUMANS AND IN VETERINARY MEDICINE | BEECHAM GROUP LIMITED (GB) | 1982-01-26 | — | — | US | claimed |
| EP-0026611-A1 | Antibacterial sulphonamides, processes for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1981-04-08 | — | — | EP | claimed |
| CN-121449877-A | Polyether surfactant and preparation method thereof | 山东悦达新材料股份有限公司 | 2026-02-03 | — | — | CN | disclosed |
| CN-115038697-A | Therapeutic agents and methods of treatment | 佛罗里达大学研究基金公司 | 2022-09-09 | — | — | CN | disclosed |
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |
| EP-0026611-B1 | ANTIBACTERIAL SULPHONAMIDES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1984-02-01 | — | — | EP | disclosed |
| US-4312867-A | USED FOR HUMANS AND IN VETERINARY MEDICINE | BEECHAM GROUP LIMITED (GB) | 1982-01-26 | — | — | US | disclosed |
| EP-0026611-A1 | Antibacterial sulphonamides, processes for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1981-04-08 | — | — | EP | disclosed |